communicable diseases

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

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Study Counts

Type	Study_count
Total_Studies	2488
interventional	1788
Observational	656
Registry	44

Studies over Time

```

Interventional Trials

Intervention Type

intervention_type	Study_Count
Drug	816
Drug|placebo	201
Other	137
Biological	131
Device	70
Behavioral	69
Procedure	68
Biological|placebo	42
Dietary Supplement|placebo	33
Dietary Supplement	30
Drug|Other	30
Diagnostic Test	18
Drug|Procedure	17
Device|Other	15
Biological|Drug	10
Biological|Other	8
Device|Drug	7
Other|Procedure	7
Other|placebo	6
Drug|Other|placebo	5
Behavioral|Drug	4
Device|Procedure	4
Dietary Supplement|Drug	4
Dietary Supplement|Drug|placebo	4
Behavioral|Other	3
Behavioral|Procedure	3
Biological|Drug|placebo	3
Biological|Procedure	3
Combination Product	3
Device|Drug|Other	3
Biological|Drug|Other	2
Biological|Drug|Procedure	2
Combination Product|Other	2
Diagnostic Test|Other	2
Drug|placebo|Procedure	2
Genetic	2
Behavioral|Biological	1
Behavioral|Device	1
Behavioral|Dietary Supplement|placebo	1
Behavioral|Drug|Genetic|Procedure	1
Behavioral|Drug|Other	1
Biological|Device|Drug	1
Biological|Drug|Other|placebo	1
Biological|Genetic|Other	1
Biological|Other|Procedure	1
Biological|placebo|Procedure	1
Combination Product|Diagnostic Test	1
Combination Product|Dietary Supplement|placebo	1
Device|Drug|placebo	1
Device|Drug|Procedure	1
Device|placebo	1
Diagnostic Test|Drug	1
Dietary Supplement|Other	1
Drug|Other|Procedure	1
Drug|Procedure|Radiation	1
placebo	1
placebo|Procedure	1
Procedure|Radiation	1

Count of Studies by Intervention (normalized and mapped)

Intervention_type	intervention	Study_count	Date of First Study
placebo	placebo	223	2014
Drug	vancomycin	48	2013
Drug	zidovudine	44	1999
Drug	sof	37	2014
Drug	ritonavir	28	2013
Drug	linezolid	25	2014
Drug	ribavirin	25	2010
Drug	azithromycin	24	2017
Drug	metronidazole	23	2013
Drug	meropenem	22	2013
Drug	rbv	22	2016
Drug	standard care	22	2010
Drug	vel	19	2017
Drug	amoxicillin	18	2013
Drug	clarithromycin	18	2013
Drug	lamivudine	18	2017
Drug	sof/vel	18	2017
Drug	ldv	16	2017
Drug	ldv/sof	16	2017
Drug	didanosine	15	2005
Drug	fluconazole	15	2016
Other	blood sample	14	2010
Drug	emtricitabine	14	2013
Drug	levofloxacin	14	2010
Drug	r	14	2014
Drug	tigecycline	14	2013
Drug	abt-450	13	2011
Drug	ganciclovir	13	2018
Drug	rifabutin	13	2013
Drug	daptomycin	12	2009
Drug	tazobactam	12	2017
Drug	tenofovir	12	2013
Other	laboratory biomarker analysis	11	2015
Drug	raltegravir	11	2010
Drug	ciprofloxacin	10	2019
Drug	stavudine	10	2003
Drug	acyclovir	9	2009
Drug	efavirenz	9	2015
Drug	ethambutol hydrochloride	9	1999
Drug	imipenem	9	2011
Drug	sofosbuvir	9	2014
Drug	valacyclovir	9	2013
Drug	zalcitabine	9	1999
Drug	doripenem	8	2011
Drug	itraconazole	8	2010
Drug	nevirapine	8	2005
Drug	ribavirin (rbv)	8	2014
Drug	abacavir	7	2007
Drug	abt-267	7	2014
Drug	albendazole	7	2010
Drug	aztreonam	7	2013
Drug	cilastatin	7	2011
Drug	ertapenem	7	2017
Drug	hydroxychloroquine	7	2020
Drug	kg	7	2016
Drug	maraviroc	7	2009
Drug	nelfinavir mesylate	7	2001
Drug	piperacillin	7	2018
Drug	posaconazole	7	2020
Drug	saline	7	2011
Drug	valganciclovir	7	2013
Dietary Supplement	vitamin d	7	2014
Drug	abacavir sulfate	6	2005
Drug	abt-267, abt-333	6	2013
Drug	abt-333	6	2009
Drug	abt-450/r/abt-267, abt-333	6	2013
Drug	atazanavir	6	2013
Drug	cefazolin	6	2015
Drug	ceftriaxone	6	2019
Drug	chlorhexidine gluconate	6	2010
Drug	clindamycin	6	2014
Drug	dalbavancin	6	2017
Drug	darunavir	6	2009
Drug	dasabuvir	6	2014
Drug	dolutegravir	6	2016
Drug	doxycycline	6	2019
Other	fecal microbiota transplantation	6	2017
Drug	fidaxomicin	6	2016
Drug	isoniazid	6	2007
Drug	lopinavir	6	2009
Drug	ombitasvir	6	2015
Drug	paritaprevir	6	2015
Drug	voriconazole	6	2012
Drug	vox	6	2015
Drug	3tc	5	2014
Drug	abt-450/r/abt-267	5	2014
Drug	antibiotics	5	2019
Drug	ceftolozane	5	2017
Drug	ceftriaxone sodium	5	2010
Drug	cephalexin	5	2012
Drug	chlorhexidine	5	2015
Drug	delafloxacin	5	2013
Drug	esomeprazole	5	2013
Drug	foscarnet sodium	5	1999
Drug	imipenem/cilastatin	5	2012
Biological	inactivated, split-virion influenza vaccine	5	2008
Drug	indinavir sulfate	5	2000
Drug	lopinavir/ritonavir	5	2009
Drug	mupirocin	5	2012
Drug	omeprazole	5	2017
Drug	piperacillin/tazobactam	5	2018
Drug	sargramostim	5	1999
Drug	tdf	5	2018
Drug	telavancin	5	2011
Drug	tenofovir disoproxil fumarate	5	2017
Drug	trimethoprim	5	2020
Biological	a	4	2015
Drug	aldesleukin	4	2000
Drug	cefepime	4	2015
Drug	ceftaroline	4	2015
Drug	ceftobiprole	4	2009
Drug	cefuroxime	4	2010
Drug	clofazimine	4	1999
Biological	convalescent plasma	4	2020
Drug	ergoferon	4	2016
Drug	hydroxyurea	4	1999
Drug	lamivudine (3tc)	4	2016
Drug	losartan	4	2012
Drug	mk0826, ertapenem sodium	4	2004
Drug	nitrofurantoin	4	2010
placebo	placebo for ribavirin	4	2013
placebo	placebo for vrc01	4	2015
Drug	soc	4	2013
Drug	sof/vel/vox	4	2015
Drug	sulfamethoxazole	4	2017
Drug	telmisartan	4	2014
Drug	temocillin	4	2015
Drug	thalidomide	4	1999
Drug	trimethoprim-sulfamethoxazole	4	2008
Biological	vrc01	4	2015
Drug	abacavir/lamivudine	3	2004
Drug	abt-493	3	2015
Drug	abt-493/abt-530	3	2015
Drug	abt-530	3	2015
Biological	alhydrogel	3	2013
Drug	amprenavir	3	1999
Drug	antibiotic	3	2011
Behavioral	audit	3	2017
Biological	b	3	2015
Drug	best available therapy	3	2016
Dietary Supplement	bifidobacterium animalis subsp. lactis	3	2012
Biological	biological samples	3	2020
Procedure	blood draw	3	2009
Drug	boceprevir	3	2012
Drug	caspofungin acetate	3	2011
Drug	ceftaroline fosamil	3	2011
Drug	ceftazidime	3	2009
Drug	ceftazidime - avibactam ( caz-avi)	3	2012
Drug	ceftobiprole medocaril	3	2017
Drug	cipro xr (ciprofloxacin, bayq3939)	3	2007
Drug	clavulanate	3	2014
Drug	clavulanic acid	3	2008
Drug	comparator: ceftriaxone sodium	3	2009
Behavioral	control	3	2019
Biological	cranberry juice	3	2013
Drug	dapsone	3	1999
Drug	dexamethasone	3	2011
Drug	dtg	3	2016
Drug	emtricitabine (tdf	3	2016
Drug	eravacycline	3	2017
Drug	ertapenem sodium	3	2010
Drug	everolimus	3	2012
Drug	fosamprenavir	3	2008
Drug	gepotidacin	3	2018
Drug	gsk1349572	3	2010
Other	hand sanitizer	3	2012
Drug	heparin	3	2016
Behavioral	household cleaning	3	2015
Drug	ingavirin	3	2017
Drug	iv vancomycin	3	2010
Drug	lamivudine/zidovudine	3	2001
placebo	linezolid placebo	3	2015
Drug	mebendazole	3	2014
Drug	moxifloxacin (avelox, bay12-8039)	3	2010
Other	no intervention	3	2015
Drug	omadacycline	3	2016
Drug	ombitasvir/paritaprevir/ritonavir	3	2014
Drug	ombitasvir/paritaprevir/ritonavir/dasabuvir	3	2015
Drug	oritavancin	3	2015
placebo	placebo for abt-333	3	2009
Drug	plazomicin	3	2013
Dietary Supplement	probiotics	3	2011
Drug	pyridoxine hydrochloride	3	1999
Drug	rbx2660	3	2017
Drug	ridinilazole	3	2018
Drug	rifampicin	3	2017
Drug	rifampin	3	1999
Other	standard wound care	3	2019
Drug	sulbactam	3	2016
Drug	sulfamethoxazole-trimethoprim	3	1999
Drug	telaprevir	3	2013
Drug	trimethoprim/sulfamethoxazole	3	2012
Drug	valacyclovir hydrochloride	3	1999
Device	vicryl plus	3	2009
Drug	NA	2	2011
Drug	160 mg of sulfamethoxazole	2	2012
Drug	2% chlorhexidine gluconate cloth	2	2018
Drug	2% mupirocin ointment	2	2008
Biological	30 âµg	2	2016
Biological	30 âµg/strain of quadrivalent vlp vaccine	2	2016
Biological	a/h5n1 inactivated, split virion pandemic influenza vaccine	2	2009
Drug	ab103 0.5 mg	2	2011
Drug	ab103 0.5 mg/kg	2	2011
Drug	abc	2	2014
Drug	amox	2	2015
Drug	amoxicillin/clavulanate	2	2014
Drug	amphotericin b	2	1999
Drug	antistaphylococcal penicillin	2	2004
Drug	at-527	2	2019
Behavioral	audit/feedback: peer comparison	2	2011
Drug	avelox (moxifloxacin, bay12-8039)	2	2009
Drug	azli	2	2017
Biological	bezlotoxumab	2	2017
Drug	bismuth-containing quadruple therapy (rabeprazole, tripotassium dicitrate bismuthate, metronidazole, tetracycline)	2	2015
Procedure	blood collection	2	2015
Drug	capravirine	2	1999
Drug	caz-avi	2	2013
Drug	cd4-igg	2	1999
Behavioral	cds order sets: suggested alternatives	2	2011
Drug	cefiderocol	2	2019
Drug	cefixime	2	2019
Drug	cefotaxime	2	2016
Drug	ceftazidime -avibactam	2	2015
Biological	cervarix	2	2017
Drug	chlorhexidine-alcohol	2	2018
Device	chlorhexidine-impregnated foam dressing	2	2007
Drug	clotrimazole	2	1999
Biological	cmv	2	2018
Drug	cmx001	2	2009
Drug	cmx157	2	2016
Drug	co-amoxiclav	2	2018
Drug	coated vicryl plus	2	2020
Drug	cobicistat	2	2017
Drug	colistin	2	2013
Drug	comparator	2	2016
Drug	cotrimoxazole	2	2017
Drug	crofelemer	2	1999
Drug	cxa-101	2	2009
Drug	cxa-201	2	2011
Drug	d-plex	2	2016
Drug	daclatasvir	2	2019
Other	dietary intervention	2	2019
Behavioral	disinfection	2	2007
Drug	dolutegravir (dtg)	2	2016
Drug	dornase alfa	2	2011
Drug	duration of treatment : 8 weeks	2	2007
Drug	duration of treatment: 14 days	2	2007
Drug	ebr	2	2017
Behavioral	educational material	2	2019
Drug	either switch to oral therapy: 500 mg of ciprofloxacin (oral)	2	2012
Drug	enfuvirtide	2	2015
Drug	enfuvirtide [fuzeon]	2	2006
Drug	entecavir	2	2015
Drug	epclusa	2	2018
Drug	ethanol	2	2009
Drug	f	2	2016
Drug	fecal microbiota transplant	2	2017
Biological	fecal microbiota transplant (fmt)	2	2016
Behavioral	feedback	2	2017
Behavioral	feedback: peer comparison	2	2011
Dietary Supplement	fermented milk	2	2013
Drug	foscarnet	2	2016
Drug	fosfomycin	2	2017
Drug	fosfomycin-trometamol	2	2013
Drug	ftc fdc)	2	2016
Drug	gentamicin	2	2016
Drug	gentamicin-collagen sponge dipped in saline	2	2008
Drug	gentamicin sulfate	2	2018
Drug	gs-9190	2	2010
Drug	gsk1265744 30 mg	2	2012
Biological	h5n1 inactivated, split virion pandemic influenza vaccine	2	2009
Drug	haart	2	2008
Other	health information prescription	2	2010
Biological	hiberixâ„¢ vaccine	2	2009
Drug	high-dose dual therapy (rabeprazole, amoxicillin)	2	2015
Biological	high dose of quadrivalent vlp vaccine	2	2014
Drug	highly active antiretroviral therapy (haart)	2	2008
Biological	hiv-1 immunogen	2	1999
Behavioral	hygiene protocol	2	2008
Drug	imi	2	2017
Drug	imipenem-cilastatin	2	2018
Drug	imipenem/cilastatin/relebactam	2	2015
Other	infectious disease specialist advice	2	2010
Biological	influenza virus vaccine usp trivalent types a	2	2008
Biological	influenza virus vaccine usp trivalent types a/b	2	2008
Drug	interferon alfa-2a	2	1999
Drug	interferon alfa-2b	2	1999
Drug	interferon alfa-n1	2	1999
Drug	interleukin-12	2	1999
placebo	intravenous placebo	2	2020
Drug	ivermectin	2	2020
Combination Product	lactobacillus reuteri	2	2012
Dietary Supplement	lactobacillus rhamnosus gg	2	2015
Drug	lansoprazole	2	2019
Biological	lbvh0101 (hib vaccine)	2	2009
Drug	letermovir	2	2018
Procedure	leukapheresis	2	2001
Drug	levo	2	2015
Drug	lexiva (gw433908)	2	2004
Biological	low dose of quadrivalent vlp vaccine	2	2014
Biological	lyophilized fecal microbiota transplantation	2	2019
Drug	maxipim	2	2018
Other	medical thoracoscopy	2	2016
Biological	medium dose of quadrivalent vlp vaccine	2	2014
Procedure	microdialysis catheter insertion	2	2015
Biological	mk-3415a	2	2012
Biological	mk-6072	2	2012
Drug	mk-7625a 1.5 g (ceftolozane 1 g	2	2016
Drug	mk-7625a 1.5 g (ceftolozane 1 g/tazobactam 0.5 g)	2	2016
Drug	mk0826,	2	2007
Drug	mk0826, /duration of treatment : 8 weeks	2	2007
Device	mngs for pathogen detection	2	2019
Drug	moxifloxacin	2	2009
Drug	mucinex	2	2012
Drug	mupirocin calcium ointment, 2%	2	2011
Drug	mupirocin ointment	2	2015
Device	negative pressure wound therapy	2	2013
Drug	nitric oxide	2	2020
Drug	nystatin	2	1999
Drug	or switch to oral therapy: 800 mg	2	2012
Drug	or switch to oral therapy: 800 mg/160 mg of sulfamethoxazole/trimethoprim (oral)	2	2012
Drug	oral vancomycin	2	2018
Device	pack-cxl	2	2016
Biological	palivizumab	2	2009
Drug	peginterferon alfa-2a	2	2010
Drug	pegylated interferon	2	2009
Drug	pegylated interferon alfa-2a	2	2011
Drug	penn microbiome therapy - 001	2	2019
Drug	penn microbiome therapy - 002	2	2019
Drug	penn microbiome therapy - 003	2	2019
Biological	pennvax-b	2	2010
Drug	pentamidine isethionate	2	1999
Drug	piperacillin-tazobactam	2	2016
placebo	placebo for abt-450	2	2012
Drug	placebo for abt-450/r/abt-267	2	2012
placebo	placebo juice	2	2013
placebo	placebo maltodextrin	2	2018
placebo	placebo matching gepotidacin	2	2019
placebo	placebo matching nitrofurantoin	2	2019
Biological	pneumococcal conjugate vaccine, heptavalent	2	1999
Biological	pneumococcal vaccine formulation 1	2	2011
Biological	pneumococcal vaccine formulation 2	2	2011
Biological	pneumococcal vaccine formulation 3	2	2011
Biological	pneumococcal vaccine, polyvalent (23-valent)	2	1999
Drug	prebiotics	2	2019
Drug	presatovir	2	2014
Device	prevena incision management system	2	2016
Drug	pro 2000	2	2005
Dietary Supplement	probiotic	2	2014
Diagnostic Test	procalcitonin	2	2017
Drug	pyrazinamide	2	1999
Biological	quadrivalent vlp vaccine	2	2018
Other	quality-of-life assessment	2	2013
Other	questionnaire administration	2	2013
Drug	relebactam	2	2015
Drug	relebactam 125 mg	2	2012
Drug	relebactam 250 mg	2	2012
Drug	rifapentine	2	1999
Drug	rifaximin	2	2018
Drug	rilpivirine 25 mg	2	2012
Drug	rpv	2	2014
Procedure	saliva	2	2012
Drug	saquinavir	2	1999
Drug	ser-109	2	2017
Drug	seraprevir	2	2019
Drug	simeprevir	2	2014
Drug	single-dose iv oritavancin diphosphate	2	2010
Behavioral	smoking cessation	2	2018
Drug	sodium fusidate	2	2015
Biological	split, inactivated, trivalent influenza vaccine	2	2006
Device	standard of care dressing	2	2010
Other	standard wound dressing	2	2013
Biological	strain of quadrivalent vlp vaccine	2	2016
Procedure	supplemental perioperative oxygen	2	2013
Drug	taf	2	2016
Drug	tazobactam 0.5 g)	2	2016
placebo	tdf placebo	2	2012
Dietary Supplement	tea catechin extracts	2	2009
Drug	tedizolid	2	2015
Drug	teicoplanin	2	2013
Diagnostic Test	telehealth	2	2020
Drug	tenofovir df	2	2012
Drug	tenofovir disoproxil fumarate (tdf)	2	2007
Drug	tenofovir disoproxil fumarate/emtricitabine (tdf/ftc fdc)	2	2016
Drug	thymopentin	2	1999
Drug	topical pexiganan cream 0.8%	2	2012
placebo	topical placebo cream	2	2012
Drug	tr-701 fa	2	2011
Drug	treatment interruption	2	2015
Drug	trimethoprim (oral)	2	2012
Combination Product	triple therapy	2	2019
Drug	truvada	2	2009
Other	ultrasound	2	2012
Drug	vabomere	2	2016
Biological	vaccine	2	2017
Drug	vancomycin oral	2	2019
Drug	vancomycin/antistaphylococcal penicillin	2	2004
Drug	vancomycin/aztreonam	2	2017
Drug	vicryl	2	2009
Dietary Supplement	vitamin e	2	2019
Drug	vorinostat	2	2017
Drug	- aztreonam	1	2011
Drug	- metronidazole	1	2007
Drug	“raltegravir”	1	2015
Drug	“raltegravir”/“zidovudine”	1	2015
Drug	“zidovudine”	1	2015
Drug	) tazobactam sodium	1	2006
Other	< 10 days of antibiotics	1	2017
Drug	0.1% octenidine with 30% 1-propanol	1	2007
Drug	0.1% octenidine with 30% 1-propanol/45% 2-propanol	1	2007
Drug	0.3% gatifloxacin	1	2010
Drug	0.3% gatifloxacin/1.0% prednisolone acetate association	1	2010
Biological	0.9% normal saline	1	2008
Other	1-fermented dairy product containing the probiotic lactobacillus casei dn-114 001 (actimelâ®)	1	2010
Other	1-step tuberculin skin test (tst)	1	2009
Other	1-step tuberculin skin test (tst)/blood sampling	1	2009
Drug	1% eye drops)	1	2016
Drug	1.0% prednisolone acetate	1	2010
Drug	1.0% prednisolone acetate association	1	2010
Drug	10-day concomitant therapy	1	2008
Drug	10-day sequential therapy	1	2013
Drug	10-day sequential treatment	1	2008
Drug	10 mg	1	2014
Drug	10%povidone-iodine	1	2018
Drug	10%povidone-iodine / coated suture	1	2018
Drug	10%povidone-iodine / non-coated suture	1	2018
Drug	100 mg) fdc	1	2017
Biological	100 necator americanus l3 larvae	1	2017
Drug	10d al quadruple therapy	1	2018
Drug	10d tl quadruple therapy	1	2018
Drug	1200 mg rifamycin sv dosage	1	2018
Drug	12h	1	2018
Biological	13-valent pneumococcal conjugate vaccine	1	2009
Biological	13-valent pneumococcal conjugate vaccine (13vpnc)	1	2009
Biological	13-valent pneumococcal polysaccharide conjugate vaccine	1	2019
Biological	13-valent pneumococcal polysaccharide conjugate vaccine（crm197,tt）	1	2019
Drug	14-day hybrid treatment	1	2010
Drug	14-day sequential treatment	1	2010
Other	14 days course of antibiotic treatment	1	2014
Biological	15 âµg	1	2016
Biological	15 âµg/strain of quadrivalent vlp vaccine	1	2016
Biological	15 âµg/strain of the licensed quadrivalent vaccine	1	2016
Drug	15 mg	1	2014
Biological	150 necator americanus l3 larvae	1	2017
Drug	160 mg trimethoprim	1	1999
Drug	160 mg trimethoprim/800 mg sulfamethoxazole	1	1999
Biological	18	1	2018
placebo	18 placebo	1	2016
Biological	18 vaccine	1	2016
Biological	18 vlp as04	1	2005
Other	18f-fdg pet scans	1	2016
Other	2-non fermented dairy product (control)	1	2010
Drug	2 antibiotics	1	2015
Drug	2 dose	1	2018
Drug	2 nrtis	1	2016
Drug	2 nrtis/an ini, nnrti,/pi	1	2016
Drug	2% alcoholic chlorhexidine	1	2016
Drug	2% alcoholic chlorhexidine skin prep (skin prep)	1	2019
Drug	2% chlorhexidine	1	2018
Drug	2% chlorhexidine / coated suture	1	2018
Drug	2% chlorhexidine / non-coated suture	1	2018
Device	2% chlorhexidine gluconate (chg) cloth	1	2015
Drug	2% chlorhexidine gluconate (chg) impregnated cloths	1	2007
Drug	2% chlorhexidine gluconate impregnated cloth	1	2005
Drug	2% chlorohexidine gluconate chin to toe	1	2015
Drug	2% chlorohexidine gluconate standard of care	1	2015
Biological	20 micrograms dose h5 vlp	1	2010
Drug	200 mg eidd-2801	1	2020
Biological	2007 formulation)	1	2006
Biological	23-valent pneumococcal polysaccharide vaccine (23vps)	1	2009
Drug	24h	1	2018
Drug	250ml hes 6%	1	2012
Other	28 days of antibiotics	1	2017
Combination Product	2nrtis	1	2017
Biological	2x 50 l3 larvae infection	1	2018
Drug	3 antibiotics	1	2015
Biological	30 micrograms dose h5 vlp	1	2010
Other	30% inhaled oxygen via nasal cannula	1	2008
Combination Product	3hp	1	2017
Combination Product	3hp/dtg /2nrtis	1	2017
Drug	3m skin	1	2011
Drug	3m skin/nasal antiseptic	1	2011
Device	3mâ„¢ tegadermâ„¢ advanced iv	1	2012
Device	3mâ„¢ tegadermâ„¢ chg iv	1	2012
Device	3mâ„¢ tegadermâ„¢ chg iv/3mâ„¢ tegadermâ„¢ advanced iv	1	2012
Drug	3tc)	1	2012
Biological	3x 50 l3 larvae immunisation with albendazole treatment	1	2018
placebo	3x placebo immunisation with albendazole treatment	1	2018
Drug	4	1	2009
Drug	4% chlorhexidine gluconate soap-like solution	1	2018
Drug	4% chlorhexidine gluconate vaginal scrub	1	2018
Drug	4% chlorhexidine liquid soap	1	2008
Drug	400 mg rifamycin sv dosage	1	2018
Biological	45 micrograms dose h5 vlp	1	2010
Biological	45 micrograms non-adjuvanted h5 vlp	1	2010
Drug	45% 2-propanol	1	2007
Drug	5	1	2005
Drug	5 gel	1	2003
Biological	50 necator americanus l3 larvae	1	2017
Drug	500 mg	1	2014
Drug	6 mg	1	2014
Biological	60 âµg	1	2016
Biological	60 âµg/strain of quadrivalent vlp vaccine	1	2016
Other	68ga-citrate	1	2016
Other	68ga-citrate/18f-fdg pet scans	1	2016
Drug	7-day quadruple therapy	1	2013
Drug	7-day standard triple therapy	1	2013
Biological	7-valent pneumococcal conjugated vaccine	1	2013
Other	7 days course of antibiotic treatment	1	2014
Device	70% isopropyl alcohol embedded caps	1	2015
Drug	74% ethanol with 10% 2-propanol	1	2007
Other	80% inhaled oxygen via non-rebreather mask	1	2008
Drug	800 mg rifamycin sv dosage	1	2018
Drug	800 mg sulfamethoxazole	1	1999
Drug	9 mg	1	2014
Drug	9% nacl 500ml	1	2012
Biological	9vhpv vaccine	1	2019
Drug	a-60444	1	2005
Behavioral	a strategy based on pct guided ab therapy	1	2006
Other	a/current standard of care alone	1	2015
Biological	a/h5n1 inactivated, split-virion influenza vaccine	1	2007
Biological	a/h5n1 inactivated, split-virion influenza vaccine/adjuvant	1	2007
Biological	a/h5n1 inactivated, split-virion pandemic influenza vaccine	1	2007
Drug	aai101 combination	1	2018
Drug	ab103 0.25 mg	1	2011
Drug	ab103 0.25 mg/kg	1	2011
Drug	abacavir (abc)	1	2007
Drug	abacavir (abc)/lamivudine (3tc) / atazanavir (atv)	1	2007
Drug	abacavir (abc)/lamivudine (3tc) / atazanavir (atv) / ritonavir (/r)	1	2007
Drug	abacavir sulfate, lamivudine	1	2001
Drug	abacavir sulfate, lamivudine/zidovudine	1	2001
Drug	abacavir/lamivudine (abc/3tc)/tenofovir/emtricitabine (tdf/ftc)	1	2012
Drug	abacavir/lamivudine/efavirenz	1	2007
Other	abbreviation of treatment duration	1	2015
Drug	abc fdc	1	2015
Drug	abc/3tc	1	2014
Procedure	abdominal closure bundle	1	2018
Procedure	abdominal wall reconstruction	1	2018
Other	abhs use	1	2009
Drug	abi-1968	1	2017
Device	abs deployed	1	2015
Device	abs deployed/active	1	2015
Device	abs deployed/not active	1	2015
Procedure	absorbable suture group	1	2012
Drug	abt-450/ritonavir, abt-267	1	2012
Drug	abt-493 coformulated with abt-530	1	2016
Drug	abv (trizivir)	1	2009
Procedure	access to an antibiotic decision support system	1	2005
Biological	acellular pertussis vaccine adsorbed	1	2001
Drug	acetylsalicylic acid (aspirin, baye4465)	1	2011
Drug	activated t-lymphocytes	1	2019
Device	active	1	2015
Biological	active comparator hepatitis b vaccine	1	2010
Biological	active comparator recombinant hepatitis b vaccine.	1	2010
Drug	active control	1	2019
Device	active control, vitamin c dosing into water	1	2015
Device	active household uv water treatment device	1	2020
Procedure	active voiding trial	1	2016
Drug	acx-362e	1	2020
Biological	ad26.hpv16	1	2018
Biological	ad26.hpv18	1	2018
Biological	adch3nsmut1	1	2014
Drug	adefovir dipivoxil	1	1999
placebo	adefovir dipivoxil placebo	1	1999
Biological	adenovirus infection	1	2008
Behavioral	adherence report	1	2009
Other	adherence to hand hygiene	1	2020
Biological	adjuvant	1	2007
Procedure	adjuvant therapy	1	2006
Biological	adjuvanted high dose of quadrivalent vlp vaccine	1	2014
Biological	adjuvanted low dose of quadrivalent vlp vaccine	1	2014
Other	admission to a novel hospital ward	1	2007
Biological	adv	1	2018
Biological	adv specific t cells	1	2009
Drug	aerosolized vancomycin	1	2006
Drug	aerosolized vancomycin/gentamicin	1	2006
Drug	afabicin	1	2018
Drug	afn-12520000	1	2012
Biological	ags-v	1	2019
Biological	ags-v/vaccine	1	2019
Behavioral	aids 101 workshop	1	2006
Device	air barrier system	1	2012
Drug	albendazole 400mg	1	2011
Drug	albendazole vs.	1	2005
Drug	albendazole vs./albendazole/ivermectin treatment	1	2005
Drug	albendazole, 2 x 400mg	1	2011
Drug	alcohol	1	2009
Other	alcohol-based hand rub (abhr)	1	2009
placebo	alcohol placebo	1	2009
Diagnostic Test	alert	1	2018
Device	alexis o-ring wound retractor	1	2015
Device	alexis o retractor	1	2016
Device	algorithm for uti	1	2016
Biological	alhydrogel hookworm vaccine	1	2005
Biological	alhydrogelâ® adjuvant	1	2019
Drug	alinia (nitazoxanide)	1	2006
Drug	alirocumab	1	2017
Behavioral	all babies are equal initiative (conditional cash transfer program)	1	2019
Biological	allogeneic bk-specific cytotoxic t-lymphocytes	1	2015
Biological	allogeneic cytomegalovirus-specific cytotoxic t lymphocytes	1	2014
Procedure	allogeneic lymphocyte transfer	1	1999
Device	allograft group	1	2017
Biological	alteplase (recombinant t-pa)	1	2018
Biological	alx-0171	1	2014
Biological	alx-0171 3.0 mg	1	2016
Biological	alx-0171 3.0 mg/kg	1	2016
Biological	alx-0171 6.0 mg	1	2016
Biological	alx-0171 6.0 mg/kg	1	2016
Biological	alx-0171 9.0 mg	1	2016
Biological	alx-0171 9.0 mg/kg	1	2016
Device	amd picasso	1	2018
Drug	amikacin sulfate	1	1999
Drug	aminolaevulinic acid photodynamic therapy	1	2014
Drug	amitriptyline hydrochloride	1	1999
Procedure	amniocentesis	1	2006
Drug	amoxicillin-clavulanic acid	1	2019
Drug	amoxicillin / clavulanic acid	1	2020
Drug	amoxicillin 1.5 gr	1	2015
Drug	amoxicillin 1gr	1	2015
Drug	amoxicillin clavulanate	1	2018
Drug	amoxicillin oral tablet	1	2017
Drug	amoxicillin trihydrate	1	1999
Drug	amoxicillin/clavulanate placebo	1	2010
Drug	amoxicillin/clavulanate potassium 1gm	1	2006
Drug	amoxicillin/clavulanic acid	1	2008
Drug	amoxicillin/clavulunate potassium	1	2011
Drug	amoxicilline	1	2009
Drug	amoxicilline/clavulanic	1	2009
Drug	amphotericin b liposomal (ambisome)	1	2009
Drug	ampicillin	1	2009
Drug	ampicillin sodium	1	1999
Drug	ampicillin/sulbactam	1	2009
Drug	an ini, nnrti,	1	2016
Drug	an3365	1	2009
Drug	ana598	1	2009
Drug	anaferon for children	1	2014
Drug	anaferon for children (liquid dosage form)	1	2017
Drug	anakinra	1	2020
Drug	anidulafungin	1	2009
Drug	annona muricata	1	2014
Other	anti-infective agents	1	2013
Biological	anti-mycoplasma hominis antibodies	1	2015
Drug	anti-pseudomonas igy gargle	1	2008
Drug	anti-schistosoma regimens	1	2008
Drug	antibiotic comparator	1	2014
Biological	antibiotic concentration in pleural fluid	1	2020
Drug	antibiotic durations	1	2017
Other	antibiotic education for children in an emergency care unit	1	2009
Device	antibiotic local prophylaxis with medicated calcium sulfate beads	1	2019
Drug	antibiotic of investigator’s choice	1	2013
Behavioral	antibiotic prescription feedback	1	2012
Drug	antibiotic prophylaxis	1	2015
Behavioral	antibiotic stewardship program	1	2017
Procedure	antibiotic therapy	1	2019
Other	antimicrobial hand towel	1	2015
Device	antimicrobial impregnated catheter (5593)	1	2007
Radiation	antimicrobial photodynamic therapy	1	2017
Drug	antimicrobial solution	1	2012
Behavioral	antimicrobial stewardship	1	2019
Device	antimicrobial synthetic bone graft	1	2019
Dietary Supplement	antioxidants	1	2008
Drug	antiretroviral therapy (art) (regimen will vary within countries	1	2015
Drug	antiretroviral therapy (art) (regimen will vary within countries/by patient)	1	2015
Device	antiseptic-coated central venous catheters	1	2006
Drug	antiseptic bundle	1	2014
Biological	antiseptic substantivity	1	2011
Device	apheresis machine	1	2008
Procedure	application of a contralateral drainage (penrose â® device)	1	2013
Combination Product	applicator	1	2019
Other	aquacel silver	1	2018
Drug	ar-301	1	2018
Dietary Supplement	arabinoxylan rice bran	1	2016
Drug	arbidol	1	2020
Drug	arctuvan	1	2017
Device	aries bordetella assay	1	2016
Drug	arm 2: decolonization	1	2014
Drug	arm a: poly-iclc	1	2014
Drug	arm b: normal saline	1	2014
Drug	art at 24 weeks	1	2016
Drug	art initiation at time of hiv diagnosis	1	2016
Drug	artemether-lumefantrine 20 mg-120 mg oral tablet	1	2020
Drug	artemether lumefantrine	1	2014
Drug	artemic	1	2020
Procedure	articulating spacer	1	2011
Drug	arv regimen	1	2005
Biological	as02a vaccine	1	2005
Behavioral	ask me 3	1	2014
Drug	aspirin	1	2015
Drug	at-777	1	2020
Drug	atazanavir (atv)	1	2007
Drug	atovaquone	1	1999
Drug	atovaquone proguanil	1	2018
Drug	atriplaâ®	1	2010
Other	audit/feedback	1	2017
Drug	aurograb	1	2005
Biological	autologous dendritic cells with no mrna transfection	1	2009
Biological	autologous fecal microbiota therapy	1	2014
Behavioral	automated reminder	1	2015
Behavioral	automated reminder/script	1	2015
Drug	avibactam (avi)	1	2012
Drug	azasite (azithromycin ophthalmic solution)	1	2007
Drug	azasite eye drops	1	2007
Drug	azithromycin 1 gram	1	2012
Drug	azithromycin 250 mg	1	2017
Drug	azithromycin 500 mg oral tablet x 4	1	2019
Drug	azithromycin/placebo	1	2013
Drug	azithromycin/standard of care	1	2010
Drug	azt/3tc/abv (trizivir)	1	2009
Drug	aztreonam (atm)	1	2012
Drug	aztreonam for inhalation (ai)	1	2010
Drug	b/current standard of care/zmapp	1	2015
Combination Product	bacillus clausii	1	2018
Biological	bacterial culture of the prepared skin’s areas	1	2011
Other	bacterial culture of the prepared skin’s areas with two antiseptics	1	2013
Other	bacterial culture of the prepared skin’s areas with two antiseptics/two controls	1	2013
Drug	bacterial lysates	1	2008
Procedure	bacterial ulcer control	1	2015
Procedure	bacterial ulcer cross-linking	1	2015
Biological	bacteriological analyses on clinical samples performed with swabs	1	2017
Device	bactiguard infection protection (bip) cathter.	1	2010
Drug	bactrobanâ® nasal ong	1	2019
Other	bal fluid sampling	1	2016
Dietary Supplement	bb12	1	2008
Drug	bc-3781	1	2010
Other	bca method for assessing environmental cleanliness	1	2019
Biological	bcg	1	2013
Drug	bcx4430	1	2014
Biological	begrivacâ®	1	2009
Behavioral	behavior change communication to promote hygiene behavior	1	2019
Other	behavioral counseling	1	2007
Drug	benzoyl peroxide solution	1	2014
Drug	benzoyl peroxide solution/chlorhexidine scrub	1	2014
Drug	benztropine mesylate	1	1999
Drug	beta-lactam	1	2006
Behavioral	betadine douches	1	2018
Procedure	betadine lavage	1	2010
Drug	bifidobacterium animalis oral product	1	2017
Dietary Supplement	bifidobacterium infantis	1	2018
Drug	biktarvy	1	2018
Diagnostic Test	biofire film array gastrointestinal panel	1	2018
Other	biological samples collection of blood	1	2016
Other	biological samples collection of blood/feces	1	2016
Other	biomarker- elispot test	1	2015
Device	bionecteur	1	2014
Procedure	biopsy(ies) during high resolution anoscopy	1	2014
Drug	bismuth	1	2015
Biological	bkv specific t cells	1	2018
Other	bleach	1	2012
Other	bleach bath (dilute)	1	2013
Procedure	bleach baths (dilute)	1	2007
Other	bleach/uv-c light	1	2012
Other	blood	1	2020
Other	blood culture	1	2010
Diagnostic Test	blood cultures	1	2018
Other	blood stage malaria challenge infection, p. falciparum 3d7	1	2018
Procedure	blood testing	1	1999
Procedure	blood transfusion	1	1999
Drug	bms-650032	1	2010
Drug	bms-790052	1	2010
Biological	bms-914143 (peginterferon lambda-1a)	1	2012
Drug	bms-955176	1	2013
Biological	bnt162a1	1	2020
Biological	bnt162b1	1	2020
Biological	bnt162b2	1	2020
Biological	bnt162c2	1	2020
Drug	boceprevir, peg-interferon alfa 2b	1	2011
Drug	boceprevir, peg-interferon alfa 2b/ribavirin	1	2011
Device	bone allograft	1	2017
Device	bone auto	1	2017
Device	bone auto/allograft group	1	2017
Procedure	bone marrow transplant	1	1999
Other	booster sessions	1	2016
Drug	boswellia leaf extract	1	2014
Procedure	bowel preparation	1	2016
Diagnostic Test	breath volatile organic compounds under chemotherapy	1	2018
Other	brief intervention	1	2013
Other	brief intervention/parent leaflet	1	2013
Drug	brilacidin	1	2014
Drug	broad-spectrum antibiotics	1	2019
Drug	bromhexine hydrochloride	1	2020
Drug	btz-043	1	2018
Other	buckwheat honey	1	2010
Drug	buffergel	1	2003
Other	bundled l&d infection prevention interventions	1	2019
Drug	by patient)	1	2015
Drug	c	1	2016
Biological	c-reactive protein	1	2012
Biological	c-reactive protein/procalcitonin dosages	1	2012
Drug	c 500 mg	1	2011
Drug	cabotegravir - injectable suspension (cab la)	1	2016
Drug	cabotegravir (cab) tablet	1	2016
Drug	cabotegravir injection 3 ml (200 mg	1	2015
Drug	cabotegravir injection 3 ml (200 mg/ml) im given once on day 1.	1	2015
Drug	cabotegravir tablet 30 mg once daily for 28 days.	1	2015
Drug	cadazolid	1	2014
Drug	caffeine	1	2011
Drug	camostat mesilate	1	2020
Drug	canephronâ® n	1	2011
Drug	carboplatin	1	2006
Behavioral	care services	1	2007
Diagnostic Test	care with c-reactive protein assay in micro method	1	2018
Other	carrageenan-based gel	1	2015
Other	cash	1	2017
Other	cash transfer	1	2017
Drug	catechin extracts (health food)	1	2005
Dietary Supplement	caterpillar cereal	1	2011
Other	catheter clamping only	1	2020
Drug	catheter insertion with povidone iodine	1	2017
Device	catheter replacement	1	2017
Drug	cb-183,315	1	2010
Drug	cd4 antigens	1	1999
Biological	cd45ra-depleted peripheral blood mononuclear cells	1	2016
Drug	cefazolin in combination with either tobramycin	1	2016
Drug	cefazolin in combination with either tobramycin/gentamicin	1	2016
Other	cefazolin irrigation	1	2012
Drug	cefdinir	1	2005
Drug	cefepime/aai101 combination	1	2018
Drug	cefepime/vnrx-5133 (taniborbactam)	1	2019
Drug	cefoperazone sodium 1:1) pfizer ltd.	1	2006
Drug	cefotaxime injection	1	2019
Drug	cefotaxime/ceftriaxone	1	2019
Drug	ceftaroline fosamil/nxl104 (q12h)	1	2011
Drug	ceftaroline fosamil/nxl104 (q8h)	1	2011
Drug	ceftazidime-avibactam	1	2012
Drug	ceftazidime/nxl104 / metronidazole	1	2008
Drug	ceftolozane/tazobactam	1	2019
Drug	ceftolozane/tazobactam 1000/500 mg	1	2014
Drug	ceftolozane/tazobactam 12/6 mg/kg	1	2014
Drug	ceftolozane/tazobactam 18/9 mg/kg	1	2014
Drug	ceftolozane/tazobactam 20/10 mg/kg	1	2014
Drug	ceftolozane/tazobactam 30/15 mg/kg	1	2014
Drug	ceftriaxone / metronidazole	1	2008
Drug	ceftriaxone 2g	1	2018
Drug	ceftriaxone 2g/ 12h	1	2018
Drug	ceftriaxone 4g	1	2018
Drug	ceftriaxone 4g/ 24h	1	2018
Drug	ceftriaxone intravenous	1	2014
Drug	ceftriaxone sodium / metronidazole	1	2005
Drug	ceftriaxone sodium/sulbactam sodium for injection	1	2019
Drug	ceftriaxone/metronidazole	1	2005
Drug	cefuroxime 1.5 g intravenous	1	2015
Drug	cefuroxime/metronidazole	1	2008
Other	cell therapy	1	2011
Procedure	cement with erytromycin	1	2012
Procedure	cement with erytromycin/colistin.	1	2012
Procedure	cement without antibiotic.	1	2012
Drug	central nervous system (cns) prophylaxis	1	2007
Device	central venous catheter	1	2007
Device	centricyte 1000	1	2020
Drug	cephalexin/clindamycin/linezolid	1	2011
Drug	cephalozin	1	2014
Other	ceramic water filter	1	2012
Biological	chadv63.hivconsv	1	2014
Drug	chemotherapy	1	2019
Procedure	chest tube drainage	1	2020
Behavioral	chip	1	2019
Device	chlorhexidine-impregnated disk	1	2018
Other	chlorhexidine bathing	1	2014
Drug	chlorhexidine gluconate (chg)	1	2017
placebo	chlorhexidine gluconate (drug) vs placebo	1	2006
Drug	chlorhexidine gluconate 2% wipe	1	2018
Procedure	chlorhexidine gluconate skin cleanser	1	2013
Device	chlorhexidine impregnated patch (biopatch)	1	2011
Biological	chlorhexidine in isopropyl alcohol	1	2011
Drug	chlorhexidine scrub	1	2014
Genetic	chlorhexidine showers	1	2007
Drug	chlorhexidine sol 4%	1	2015
Drug	chlorhexidine, lifo-scrub sol 4%â®, 500ml, b. braun	1	2019
Drug	chloroquine	1	2014
Dietary Supplement	cholecalciferol	1	2012
Dietary Supplement	cholecalciferol (vitamin d	1	2010
Dietary Supplement	cholecalciferol (vitamin d/vigantol oil)	1	2010
Dietary Supplement	cholecalciferol (vitamin d3)	1	2010
Behavioral	chw tbi) program	1	2018
Drug	cilastatin 500 mg	1	2012
Drug	cimetidine	1	1999
Drug	cipro ir (ciprofloxacin, bayq3939)	1	2008
Drug	ciprofloxacin 750 mg oral	1	2015
Drug	ciprofloxacin hydrochloride	1	1999
Drug	ciprofloxacin/cefazolin //- metronidazole	1	2007
Procedure	circumcision	1	2015
Drug	cisplatin	1	2019
Drug	clarithromycin 1000 mg	1	2017
Drug	clarithromycin oral tablet	1	2017
Drug	clarithromycin, amoxicillin, omeprazole	1	2008
Drug	clarithromycin, metronidazole, amoxicillin (	1	2008
Drug	clarithromycin, metronidazole, amoxicillin (/omeprazole)	1	2008
Drug	clarythromicin 500 mg	1	2015
Procedure	classical parenteral antibiotic prophylaxis	1	2019
placebo	clavulanate placebo	1	2010
Drug	clavulanate potassium 1gm	1	2006
Drug	clavulanic	1	2009
Drug	clavulunate potassium	1	2011
Procedure	clean patient preparation for cystoscopy	1	2005
Device	click device	1	2019
Biological	clindamycin/rifampicin dosages	1	2016
Behavioral	clinical decision support (cds): accountable justifications	1	2011
Behavioral	clinical decision support: accountable justification	1	2011
Other	clinical pathway	1	2016
Drug	clinsupv3 -soft gelatin capsule	1	2012
Drug	clinsupv3er- extended release tablet	1	2012
Drug	clopidogrel	1	2015
Procedure	clorhexidine	1	2012
Device	closed incision negative pressure therapy (cinpt)	1	2017
Biological	clostridium difficile toxoid vaccine	1	2008
Biological	clostridium difficile toxoid vaccine with adjuvant	1	2008
Drug	cloxacillin	1	2009
Biological	cmv-peptide-specific t cells	1	2008
Biological	cmv-specific t-cells	1	2019
Biological	cmv-tcr-t cells	1	2019
Biological	cmv gb vaccine	1	2005
Drug	cmv hyperimmune globulin	1	2011
Other	cmv pcr	1	2014
Biological	cmv specific adoptive t-cells	1	2016
Biological	cmv specific t-cells	1	2019
Biological	cmv/adv /ebv/bkv specific t cells	1	2018
Biological	cmv/adv specific t cells	1	2009
Biological	cmvpp65 specific t-cells	1	2014
Drug	co-trimoxazole; tmp-smz	1	2005
Other	coaching program	1	2015
Drug	coated suture	1	2018
Drug	coated vicryl	1	2020
Dietary Supplement	cold-fx	1	2005
Dietary Supplement	cold-fx natural health product	1	2005
Drug	colistimethate sodium	1	2018
Drug	colistimethate sodium (cms)	1	2015
Procedure	colistin.	1	2012
Device	collagen-gentamicin sponge	1	2011
Procedure	collagen cross-linking	1	2013
Other	collection of blood samples for pk testing	1	2011
Drug	collection of fluid samples	1	2018
Other	collection of nosocomial infections	1	2016
Procedure	colonization swab samples	1	2009
Procedure	colorectal surgery	1	2015
Drug	combination of aztreonam - avibactam (atm-avi)	1	2012
Biological	combined heptavalent pneumococcal conjugate vaccine	1	2005
Biological	combined heptavalent pneumococcal conjugate vaccine/trivalent inactivated influenza vaccine	1	2005
Drug	combivir	1	2004
placebo	comfort bath cloths (placebo cloths)	1	2007
Behavioral	communidades positivas (cpos)	1	2008
Other	community based	1	2008
Behavioral	community event	1	2019
Behavioral	community health worker intervention	1	2017
Drug	comparator : piperacillin sodium (	1	2006
Drug	comparator : piperacillin sodium (/) tazobactam sodium /duration of treatment : 8 weeks	1	2006
Drug	comparator: ceftriaxone	1	2005
Drug	comparator: ceftriaxone / metronidazole	1	2005
Drug	comparator: ceftriaxone sodium / duration of treatment: 8 weeks	1	2007
Drug	comparator: ceftriaxone sodium /duration of treatment: 14 days	1	2007
Biological	comparator: hpv 16 l1 vaccine	1	2006
Drug	comparator: metronidazole	1	2007
Drug	comparator: metronidazole / duration of treatment: 8 weeks	1	2007
Drug	comparator: micafungin sodium	1	2008
Drug	comparator: piperacillin	1	2005
Drug	comparator: piperacillin/tazobactam / duration of treatment - 24 weeks	1	2005
placebo	comparator: placebo	1	2006
Drug	comparator: ticarcillin	1	2004
Drug	comparator: ticarcillin/clavulanate	1	2004
Drug	comparator: vancomycin	1	2008
Procedure	comparison of screening methods	1	2013
Other	computerized decision support	1	2017
Other	computerized decision support/audit/feedback	1	2017
Drug	concentrated herbal extract granules tra	1	2020
Drug	concomitant therapy	1	2018
Other	conditional cash transfer condition	1	2018
Drug	conjugated estrogen	1	2020
Drug	conjugated estrogen vaginal cream	1	2013
Other	consumption of heat-sterilized kombucha	1	2019
Other	consumption of kombucha	1	2019
Other	contact isolation	1	2008
Drug	contezolid acefosamil	1	2018
Other	continue triple arvs	1	2010
Drug	continued standard of care with tenofovir in addition to emtricitabine	1	2008
Drug	continued standard of care with tenofovir in addition to emtricitabine/lamivudine	1	2008
Other	continuing antibiotic therapy	1	2016
Device	continuous sternal block	1	2008
Device	continuous topical triple-tube irrigation	1	2013
Device	continuous topical triple-tube irrigation/suction	1	2013
Other	control gel	1	2015
Behavioral	control group audio jingles	1	2019
Device	conveen uncoated	1	2006
Procedure	conventional endodontic treatment	1	2017
Drug	conventional glycemic	1	2013
Other	conventional sterile dry wound dressing	1	2013
Other	copper-alloy surfaced objects	1	2012
Other	copper-alloy surfaced patient care objects	1	2012
Other	copper impregnated maternity pads	1	2017
Other	copper impregnated wound dressing	1	2017
Procedure	cord blood sample	1	2010
Drug	corticosteroids (prednisolone acetate 0.5%	1	2016
Drug	corticosteroids (prednisolone acetate 0.5%/1% eye drops)	1	2016
Biological	cp101	1	2018
Biological	cpg 10104	1	2017
Drug	cranberry	1	2006
Other	cranberry-lingonberry juice	1	2013
Drug	cranberry capsules	1	2018
Drug	cranberry powder capsules	1	2011
Dietary Supplement	cranberry type a pro anthocyandines	1	2010
Drug	cravit-based sequential therapy	1	2009
Drug	crv431	1	2018
Drug	csaac	1	2018
Drug	csac	1	2018
Drug	cse-1034 (ceftriaxone	1	2018
Drug	cse-1034 (ceftriaxone / sulbactam / edta)	1	2018
Procedure	csvf	1	2020
Diagnostic Test	ct-scan	1	2016
Behavioral	cultural adaptation of a patient-provider communication tool	1	2020
Procedure	culture	1	2006
Other	culture swabs, rodac plate cultures	1	2010
Other	cups	1	2017
Other	cups/cash	1	2017
Drug	current standard of care	1	2015
Other	current standard of care alone	1	2015
Drug	current standard of care in kenya	1	2007
Behavioral	current standard pd training	1	2018
Combination Product	cutimed	1	2018
Drug	cvt-e002 (cold-fx); a natural health product	1	2005
Drug	cvt-e002 ginseng extract	1	2005
Drug	cxa-101/ tazobactam/metronidazole	1	2010
Drug	cxa-201/metronidazole	1	2011
Drug	cycloplegic agents (cyclopentolate 1% eye drops)	1	2016
Drug	cystoscopic fluid	1	2017
Drug	cystoscopic fluid containing neosporin g. u. irrigant	1	2017
Drug	cystoscopic fluid/placebo	1	2017
Procedure	cystoscopy	1	2017
Procedure	cytokine therapy	1	2005
Procedure	cytology specimen collection procedure	1	2016
Drug	cytotoxic t-lymphocytes	1	2017
Biological	cytotoxic t lymphocytes	1	2012
Drug	cytotoxic t lymphocytes (ctls).	1	2013
Dietary Supplement	d mannose	1	2013
Drug	d_plex	1	2018
Device	dacc-coated post operative dressing	1	2016
Device	dacc impregnated dressing	1	2014
Dietary Supplement	daily multi micronutrient supplement	1	2011
Other	daily review	1	2010
placebo	dalbavancin-matching placebo	1	2014
Drug	dalbavancin single dose	1	2016
Drug	dalbavancin two dose	1	2016
Drug	daptomycin 4 mg	1	2008
Drug	daptomycin 4 mg/kg	1	2008
Drug	daptomycin 6 mg	1	2008
Drug	daptomycin 6 mg/kg	1	2008
Drug	daptomycin 6mg	1	2005
Drug	daptomycin 6mg/kg/day	1	2005
Drug	daptomycin for injection	1	2018
Drug	darunavir-cobicistat	1	2016
Drug	darunavir; ritonavir; emtricitabine	1	2009
Drug	darunavir; ritonavir; emtricitabine/tenofovir	1	2009
Drug	das181	1	2019
Drug	das181 covid-19	1	2019
Drug	das181 ol	1	2019
Device	dav132	1	2018
Drug	day	1	2005
Biological	day 140	1	2018
Dietary Supplement	day)	1	2014
Drug	dcvax-001	1	2010
Drug	debio 1450	1	2016
Drug	debio 1450 iv	1	2015
Drug	debio 1450 oral	1	2015
placebo	debio 1450 oral placebo	1	2015
Behavioral	debunking misinformation through audio dramas	1	2019
Procedure	delayed primary closure	1	2015
Other	delegation form	1	2010
Biological	dendritic cell vaccine	1	2006
Other	depletion	1	2005
Device	dermabond	1	2016
Combination Product	descovy	1	2019
Combination Product	descovy/dolutegravir	1	2019
Procedure	device replacement(pocket capsule removal)	1	2014
Drug	dexlansoprazole based triple therapy	1	2015
Drug	dextrose 5% in water	1	2010
Other	diagnosis	1	2016
Other	diagnosis, treatment	1	2009
Other	diagnosis, treatment/education	1	2009
Biological	diagnostic performances of a combination of biomarkers	1	2017
Other	dialogue tool	1	2018
Other	diaper incentive	1	2018
Drug	dicloxacillin	1	2002
Diagnostic Test	differential (cbc)	1	2018
Drug	dinitrochlorobenzene	1	1999
Biological	diphtheria	1	2001
Biological	diphtheria/tetanus toxoids/acellular pertussis vaccine adsorbed	1	2001
Drug	dipyridamole	1	2020
Other	discontinuation of prophylactic drugs i.e. co-trimoxazole, dapsone, fluconazole, itraconazole, azithromycin	1	2011
Other	discontinue tmp	1	2011
Other	discontinue tmp/smz prophylaxis	1	2011
Other	discontinue triple arvs	1	2010
Other	discontinuing antibiotic therapy	1	2016
Device	disposable negative wound pressure device (pico)	1	2018
Behavioral	distance learning package for general practitioners	1	2006
Behavioral	distance learning package for practice assistants	1	2006
Behavioral	distribution of local antibiotic guidelines	1	2005
Biological	dna plasmid encoding interleukin-12 ino-9012	1	2016
Drug	dolutegravir 50 mg	1	2017
Drug	dolutegravir/abacavir/lamivudine fdc	1	2013
Biological	donor-derived cmvpp65-specific t cells	1	2016
Biological	donor derived cytomegalovirus specific t lymphocytes	1	2016
Other	donor milk	1	2017
Drug	doripenum	1	2005
Biological	dosage of the umbilical cord blood procalcitonin for diagnosing of ibnp	1	2016
Drug	doxy	1	2018
Drug	doxycycline 200 mg	1	2015
Drug	doxycyline hyclate tablet	1	2010
Device	dr. chip hpv genotyping ivd kit	1	2020
Procedure	drainage	1	2015
Drug	drug conversion to sirolimus	1	2016
Drug	dtg 50 mg	1	2014
Drug	dtg/3tc/abc fdc	1	2015
Drug	dtg/rpv fdc	1	2016
Diagnostic Test	dual-priming oligonucleotide-based multiplex (dpo)-pcr test	1	2019
Device	dual focus with narrow band imaging	1	2019
Drug	dual therapy	1	2019
Drug	duloxetine 60 mg, qd	1	2007
Procedure	duodenal biopsy	1	2017
Device	duraderm	1	2018
Other	duration of antibiotic treatment	1	2013
Drug	duration of standard antibiotic therapy	1	2019
Drug	duration of treatment - 24 weeks	1	2005
Drug	duration of treatment: 8 weeks	1	2007
Drug	e	1	2016
Biological	e. coli 83972	1	2009
Biological	e. coli strain e1392-75-2a	1	2015
Biological	e.coli bioconjugate vaccine	1	2014
Drug	e/c/f/taf	1	2016
Drug	ebr/gzr	1	2017
Drug	ebr/gzr (50 mg/100 mg) fdc	1	2017
Biological	ebv	1	2018
Drug	echinacea	1	2011
Drug	echinacea purpurea alcoholic extract	1	2018
Drug	ecn-suspension	1	2016
Drug	edp-514	1	2019
Drug	edta)	1	2018
Other	education	1	2009
Behavioral	educational intervention	1	2006
Behavioral	educational intervention on antibiotic prescribing	1	2010
Behavioral	educational intervention program	1	2006
Drug	efavirenz 600 mg	1	2012
Drug	efavirenz, emtricitabine,	1	2009
Drug	efavirenz, emtricitabine,/tenofovir	1	2009
Drug	efv	1	2015
Drug	efv 600 mg	1	2014
Drug	efv only	1	2015
Drug	elbasvir	1	2014
Drug	elbasvir 50 mg, zepatierâ®	1	2018
Biological	electroporation-mediated plasmid dna vaccine therapy	1	2016
Drug	ellagic acid	1	2014
Drug	ellagic acid / annona muricata	1	2014
Drug	eltrombopag	1	2018
Drug	elvitegravir	1	2016
Drug	elvitegravir, cobicistat, emtricitabine,	1	2007
Drug	elvitegravir, cobicistat, emtricitabine,/tenofovir alafenamid fumarate	1	2007
Drug	elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide/other medically-appropriate fda-approved antiretroviral therapy	1	2016
Device	emdogainâ®	1	2015
Biological	emm75 streptococcus pyogenes (gas m75, strain 611024)	1	2017
Drug	emtricitabine-tenofovir	1	2016
Drug	emtricitabine-tenofovir disoproxil fumarate (truvada [trv])	1	2010
Drug	emtricitabine-tenofovir disoproxil fumarate (truvada [trv]) tail	1	2010
Drug	emtricitabine / tenofovir	1	2020
Drug	emtricitabine 200mg	1	2010
Drug	emtricitabine 200mg /tenofovir 300mg	1	2010
Drug	emtricitabine fdc	1	2013
Drug	emtricitabine/tenofovir df	1	2006
Drug	emtricitabine/tenofovir disoproxil fumarate	1	2003
Drug	emtricitabine/tenofovir disoproxil fumarate (ftc/tdf)	1	2007
Drug	emtricitibine	1	2008
Device	endoscopy	1	2020
Drug	engerix-b	1	2017
Drug	engerix b	1	2015
Other	engineered room	1	2015
Behavioral	enhanced antimicrobial stewardship commitment	1	2017
Behavioral	enhanced antimicrobial stewardship commitment/feedback	1	2017
Behavioral	enhanced education	1	2019
Behavioral	enhanced partner therapy (ept)	1	2008
Drug	entecavir with continued standard of care antiretroviral therapy	1	2008
Biological	env 2-3	1	1999
Drug	epivir	1	2004
Drug	eradication therapy (amoxicillin; esomeprazole; tinidazole; levofloxacin)	1	2012
Drug	ertapenem 1000 mg	1	2019
Drug	ertapenem intravenous	1	2007
placebo	ertapenem placebo	1	2010
Drug	ertapenem sodium (mk0826)	1	2009
Drug	erythromycin	1	2013
Drug	esomeprazole/amox/levo	1	2015
Drug	esomeprazole/amox/levo/tetra	1	2015
Drug	estradiol	1	2020
Drug	estradiol ring	1	2013
Drug	estring vaginal ring	1	2019
Drug	estrogen therapy	1	1999
Drug	ethambutol	1	2017
Drug	ethanol-lock	1	2017
Drug	etravirine	1	2010
Drug	etravirine (intelence)	1	2009
Drug	etv	1	2019
Device	eus-guided fistulization axios	1	2018
Device	eutrophill	1	2010
Behavioral	evidence-based practice for improving quality (epiq) method	1	2015
Biological	ex vivo-activated autologous lymph node lymphocytes	1	2015
Device	ex vivo lung perfusion	1	2019
Behavioral	exercise	1	2010
Biological	expanded nk cells	1	2020
Behavioral	expanded school-based handwashing promotion	1	2010
Behavioral	experimental	1	2010
Biological	experimental recombinant hepatitis b vaccine	1	2010
Biological	experimental recombinant hepatitis b vaccine, hbig	1	2010
Biological	experimental: split-virion, adjuvanted h1n1 vaccine of 15 î¼g	1	2009
Biological	experimental: split-virion, adjuvanted h1n1 vaccine of 30 î¼g	1	2009
Biological	experimental: split-virion, adjuvanted h1n1 vaccine of 7.5 î¼g	1	2009
Biological	experimental: split-virion, non-adjuvanted h1n1 vaccine of 15 î¼g	1	2009
Behavioral	explanation of peer navigator	1	2017
Behavioral	explanation of peer navigator/session wrap (5 minutes)	1	2017
Drug	extended	1	2016
Drug	extended antibiotics	1	2018
Other	extended pap	1	2017
Drug	extra dosage - cefuroxime (750mg) i.v	1	2015
Drug	ezetimibe 10mg oral tablet	1	2019
Drug	f/r/taf	1	2016
Drug	f/taf	1	2016
Drug	f/taf placebo	1	2016
Drug	f/tdf	1	2016
Drug	f/tdf placebo	1	2016
Drug	f901318	1	2018
Behavioral	facilitated referral	1	2009
Drug	factive iv	1	2013
Drug	factiveâ® tab	1	2013
Drug	factiveâ® tab / factive iv	1	2013
Procedure	faecal transplantation	1	2019
Drug	failing arv regimen	1	2019
Drug	famotidine	1	2009
Other	fast track foley removal	1	2017
Other	fasting	1	2016
Drug	favipiravir	1	2020
Diagnostic Test	fda-cleared naats	1	2019
Biological	fecal microbiota transplantation (fmt)	1	2016
Biological	fecal swab	1	2020
Diagnostic Test	fecal volatile organic compounds under chemotherapy	1	2018
Other	feces	1	2016
Other	feedback reports	1	2016
Other	feedback stewardship interventions to reduce unnecessary use of antimicrobials	1	2019
Drug	fendrix	1	2015
Other	fermented dairy product containing the probiotic lactobacillus casei dn-114 001 (actimelâ®)	1	2009
Dietary Supplement	fermented quinoa	1	2019
Dietary Supplement	fermented rice	1	2013
Dietary Supplement	fermented whey concentrate	1	2019
Dietary Supplement	ferripel-3, vitamins a&d drops	1	2006
Drug	ferumoxytol	1	2015
Drug	fiacitabine	1	1999
Drug	fialuridine	1	1999
Other	fibrinolytic group	1	2016
Drug	filgrastim	1	1999
Device	filmarray pcr multiplex-pct assay	1	2020
Device	filmarrayâ„¢ gastrointestinal (gi) panel	1	2014
Drug	finafloxacin	1	2008
Drug	finafloxacin / amoxicillin	1	2008
Drug	finafloxacin / esomeprazole	1	2008
Drug	finafloxacin hydrochloride	1	2007
Diagnostic Test	final breath volatile organic compounds	1	2018
Diagnostic Test	final fecal volatile organic compounds	1	2018
Diagnostic Test	final microbiome	1	2018
Device	finger pulse oximeter	1	2013
placebo	fish oil placebo	1	2012
Procedure	fixation of the sternotomy with more than six wires	1	2007
Procedure	flexible sigmoidoscopy	1	2015
Device	flir one	1	2014
Dietary Supplement	florababy	1	2018
Biological	flulavalâ® tetra (15 âµg	1	2016
Biological	flulavalâ® tetra (15 âµg/strain)	1	2016
Drug	fluoroquinolones (besifloxacin ; ciprofloxacin ; gatifloxacin ; levofloxacin ; moxifloxacin ; ofloxacin )	1	2016
Biological	fluzoneâ® 2012-2013 formula ndc no 498281-012-50	1	2014
Biological	fluzoneâ® high-dose (60 âµg	1	2016
Biological	fluzoneâ® high-dose (60 âµg/strain)	1	2016
Other	fmt	1	2017
Biological	fmt-c	1	2019
Biological	fmt-c lactobacillus	1	2019
Biological	focetriaâ®	1	2009
Behavioral	focus on the future program	1	2009
Device	foley catheter vs self-contained valved catheter	1	2017
Dietary Supplement	follow on formula without probiotics	1	2010
Other	force gauge	1	2019
Device	forced air warming blanket	1	2016
Other	formulation buffer	1	2009
Drug	fortum (ceftazidime for injection usp) glaxo smith kline pharmaceuticals limited	1	2006
Drug	fosamprenavir/ritonavir	1	2007
Drug	fosfomycin disodium	1	2017
Drug	fosfomycin sodium intravenous	1	2014
Drug	fosmanogepix	1	2020
Other	freeze dried strawberry powder	1	2017
Drug	frio mouth rinse	1	2008
Drug	ftc	1	2017
Drug	ftc)	1	2012
Drug	ftortiazinon (tablets 300 mg) 1	1	2018
Drug	ftortiazinon (tablets 300 mg) 1/2 dose /placebo/ maxipim	1	2018
Drug	ftortiazinon (tablets 300 mg) full dose	1	2018
Drug	ftortiazinon (tablets 300 mg) full dose / maxipim	1	2018
Drug	fuganlin oral liquid	1	2015
Other	full aseptic dressing	1	2017
Drug	full boosted fosamprenavir	1	2006
Drug	full spectrum microbiota	1	2017
Procedure	fungal ulcer control	1	2015
Procedure	fungal ulcer cross-linking	1	2015
Biological	fvh1 - a dna-based influenza vaccine	1	2012
Drug	g-csf	1	2008
Drug	g-csf/dexamethasone	1	2008
Behavioral	gamble school-based handwashing promotion program	1	2010
Biological	gardasil	1	2007
Biological	gardasil 9	1	2017
Behavioral	gargling	1	2010
Dietary Supplement	gastimunhp plus	1	2019
Biological	gbs vaccine	1	2014
Drug	gene therapy method for cgd	1	1999
Biological	genevax il-12-4532	1	2008
Device	gentamicin-impregnated implants	1	2019
Device	gentamicin-impregnated implants/ sponges (sponge)	1	2019
Drug	genvoya	1	2018
Drug	genvoyaâ®	1	2018
Biological	gla-af	1	2017
Biological	gla-se	1	2013
Drug	glecaprevir	1	2019
Drug	glecaprevir 300 mg	1	2019
Drug	glecaprevir 300 mg / pibrentasvir 120 mg oral tablet	1	2019
Drug	glecaprevir/pibrentasvir (g/p)	1	2019
placebo	glizigen placebo	1	2018
Dietary Supplement	glizigenâ®	1	2018
Drug	globulin, immune	1	1999
Other	gloves	1	2011
Drug	gls-1200	1	2020
Biological	gls-6150	1	2018
Drug	gls4	1	2019
Drug	glutamine	1	2012
Biological	gne8 rgp120	1	1999
Drug	gno	1	2018
Behavioral	goal-setting (5 minutes)	1	2017
Biological	gp160 vaccine (microgenesys)	1	1999
Biological	granulocyte transfusions	1	2008
Drug	grazoprevir	1	2014
Drug	grazoprevir / elbasvir	1	2014
Drug	grazoprevir 100 mg	1	2018
Drug	grazoprevir 100 mg/ elbasvir 50 mg, zepatierâ®	1	2018
Biological	group b streptococcus trivalent vaccine	1	2011
Biological	group b streptococcus vaccine	1	2011
Drug	gs-5816	1	2014
Drug	gs-5885 tablet	1	2011
Drug	gs-9256	1	2010
Drug	gs-9451 tablet	1	2011
Drug	gs-9669	1	2013
Drug	gs-9857	1	2014
Drug	gsk1265744 10 mg	1	2012
Drug	gsk1265744 10 mg oral solution	1	2008
Drug	gsk1265744 5 mg tablet	1	2008
Drug	gsk1265744 60 mg	1	2012
Drug	gsk1322322	1	2010
placebo	gsk1322322 placebo	1	2010
placebo	gsk1349572 placebo	1	2010
Drug	gsk2140944 capsules	1	2014
Drug	gsk2140944 lyophile	1	2014
Drug	gsk2248761 formulation 1	1	2009
Drug	gsk2248761 formulation 2	1	2009
Drug	gsk2248761 formulation 2/4	1	2009
Drug	gsk2248761 formulation 3	1	2009
Drug	gsk2248761 reference formulation	1	2009
Drug	gsk2248761 wbm capsule	1	2010
Drug	gsk2248761 wbm tablet	1	2010
Drug	gsk2248761 wbm tablet formulation 1	1	2010
Drug	gsk2248761 wbm tablet formulation 2	1	2010
Drug	gsk2248761 wbm tablet formulation 3	1	2010
Drug	gsk2838232	1	2017
Drug	gsk3640254	1	2017
Drug	gsk364735	1	2006
Drug	gsk364735 oral solution	1	2006
Drug	gsk364735 oral solution/oral tablets	1	2006
Drug	gsk580416	1	2007
Drug	gsk744	1	2014
Drug	gsk744 la	1	2014
Drug	guaifenesin	1	2010
Biological	gut infection challenge with m bovis	1	2010
Drug	gw640385	1	2005
Drug	gynoclin v	1	2013
Drug	gzr	1	2017
Drug	gzr (50 mg	1	2017
Drug	h. pylori treatment	1	2005
Dietary Supplement	h2mf	1	2017
Biological	h5 vlp pandemic influenza vaccine 10 âµg	1	2009
Biological	h5 vlp pandemic influenza vaccine 20 âµg	1	2009
Biological	h5 vlp pandemic influenza vaccine 5 âµg	1	2009
Biological	h5n1 inactivated, split-virion influenza vaccine	1	2007
Biological	h5n1 inactivated, split-virion pandemic influenza vaccine	1	2007
Procedure	hair clipping	1	2009
Drug	half-boosted fosamprenavir	1	2006
Drug	halometasone triclosan	1	2017
Behavioral	hand finger nail clipping	1	2012
Behavioral	hand hygiene	1	2007
Other	hand hygiene compliance observation with video camera surveillance system	1	2019
Other	hand hygiene compliance observation with video camera surveillance system/performance feedback of the hh rates to hcws	1	2019
Other	hand hygiene implementation strategy	1	2016
Behavioral	hand hygiene improvement intervention	1	2014
Behavioral	hand hygiene promotion	1	2008
Behavioral	hand hygiene/educational material	1	2007
Behavioral	hand washing with soap	1	2012
Behavioral	hand washing with soap/hand finger nail clipping	1	2012
Behavioral	handwashing	1	2005
Behavioral	hbv vaccination self-efficacy intervention	1	2009
Drug	hcmv-specific hyperimmune globulin (cytotectâ®)	1	2009
Biological	hcv dna vaccine ino-8000	1	2016
Diagnostic Test	hcv rna self-test	1	2019
Other	health-care associated infection (hcai)	1	2017
Behavioral	health check-up for expectant moms	1	2019
Behavioral	health education intervention	1	2010
Other	health education learning package	1	2019
Behavioral	health hygiene education	1	2020
Behavioral	health promotion	1	2013
Behavioral	health promotion intervention	1	2009
Behavioral	healthy love workshop	1	2006
placebo	heparin-saline placebo	1	2011
Device	heparin impregnated central venous catheters	1	2005
Biological	hepatitis a vaccine (inactivated)	1	1999
Biological	hepatitis b vaccine (recombinant)	1	2001
Biological	hepatitis b vaccine 3 dose schedule (0,1,2 month)	1	2009
Biological	hiberix (haemophilus influenzae type b (hib) vaccine)	1	2009
Biological	high-dose inactivated, split-virion influenza vaccine	1	2006
Biological	high dose of h5 vlp vaccine	1	2013
Biological	high dose of h5 vlp vaccine / alhydrogel	1	2013
Biological	high dose of h5 vlp vaccine / gla-se	1	2013
Biological	high dose of h7 vlp vaccine	1	2013
Biological	high dose of h7 vlp vaccine / alhydrogel	1	2013
Drug	high dose vitamin d	1	2010
Procedure	high resolution anoscopy	1	2014
Procedure	high resolution anoscopy biannually	1	2014
Dietary Supplement	high strength cranberry	1	2017
Drug	highly active antiretroviral therapy	1	2007
Behavioral	hiv	1	2006
Biological	hiv-1	1	1999
Device	hiv-1 antibody test kit	1	2007
Diagnostic Test	hiv-1 rna testing	1	2018
Biological	hiv-1 sf-2	1	1999
Biological	hiv-1mn	1	1999
Biological	hiv gp120	1	2005
Biological	hiv gp120/neftat/as02a vaccine	1	2005
Behavioral	hiv prevention intervention - project prissma - hiv i have my eye on you	1	2009
Behavioral	hiv prevention scripted lesson plans	1	2019
Behavioral	hiv testing	1	2007
Behavioral	hiv testing/care services	1	2007
Behavioral	hiv/aids 101 workshop	1	2006
Behavioral	hombres: a lay health advisor approach to std prevention	1	2005
Other	home-cov rule implementation	1	2020
Other	homefirst	1	2015
Behavioral	household cleaning/disinfection	1	2007
Biological	hpv-16	1	2016
Biological	hpv-16/18 placebo	1	2016
Biological	hpv-16/18 vaccine	1	2016
Biological	hpv 16	1	2005
Biological	hpv 16/18 vlp as04	1	2005
Procedure	hpv detection in anal canal samples	1	2016
Drug	hs-10234	1	2019
Biological	human fecal matter	1	2013
Biological	human papillomavirus 9-valent vaccine, recombinant	1	2020
Drug	human recombinant deoxyribonuclease (dnase)	1	2018
Biological	hxtc	1	2017
Device	hyalofemme	1	2019
Drug	hybrid regimen	1	2019
Drug	hybrid therapy	1	2018
Procedure	hydrogen peroxide pretreatment group	1	2014
Drug	hydroxychloroquine sulfate tablets	1	2020
Drug	hydroxychloroquine sulfate tablets/lopinavir/ ritonavir oral tablets	1	2020
Other	hygiene	1	2010
Behavioral	hygienic recommendations	1	2019
Device	ialuril	1	2019
Drug	ibuprofen	1	2011
Procedure	icd	1	2008
Procedure	icd/pacemaker pocket revision	1	2008
Behavioral	identifying	1	2017
Behavioral	identifying/prioritizing needs (5 minutes)	1	2017
Drug	iff flavor 316 282, paracetamol , phenylephrine, guaifenesin	1	2012
Biological	ifn-î³ positive selected t-cells	1	2013
Diagnostic Test	igg antibody test	1	2020
Diagnostic Test	igm/igg rapid test	1	2020
Biological	iiv	1	2014
Biological	il-15 adjuvant	1	2008
Drug	ilaprazole	1	2015
Drug	ilaprazole / amoxicillin	1	2015
Drug	im-01	1	2019
Device	imaging	1	2005
Drug	imatinib	1	2020
Drug	imi/rel	1	2019
Drug	imi/rel fdc	1	2017
Drug	imipenem / cilastatin	1	2011
Drug	imipenem/cilastatin 500 mg	1	2012
Drug	immediate-release guaifenesin	1	2012
Biological	immunization with inactivated bacteria	1	2005
Biological	immunological diagnosis tests	1	2016
Dietary Supplement	impact advanced recovery	1	2018
Procedure	implantation of a static, non-articulating cement spacer.	1	2011
Procedure	implantation of an articulating spacer.	1	2011
Other	implementation of prospective audit	1	2019
Other	implementation of prospective audit/feedback stewardship interventions to reduce unnecessary use of antimicrobials/improve quality of prescriptions	1	2019
Behavioral	implementation of the ao trauma ssi prevention bundle	1	2017
Other	improve quality of prescriptions	1	2019
Device	improved “injera” baking biomass stove	1	2018
Behavioral	improved management of severe neonatal infections	1	2005
Behavioral	improving gp antibiotics prescribing behaviour	1	2013
Biological	inactivated split-virion influenza vaccine	1	2006
Biological	inactivated, split-virion, influenza vaccine	1	2008
Device	inactive household uv water treatment device	1	2020
Procedure	incision	1	2015
Procedure	incision/drainage	1	2015
Drug	indinavir	1	1999
Drug	indinavir (mk-0639)	1	1999
Other	individual homeopathic treatment	1	2011
Other	infection control measure	1	2020
Other	infection prevention bundle	1	2020
Other	influenza vaccine intervention	1	2013
Behavioral	information-matched control	1	2019
Behavioral	information pages	1	2013
Drug	ingavirin (imidazolyl ethanamide pentandioic acid)	1	2017
Drug	inhaled beclomethasone	1	2015
Drug	inhaled molgramostim	1	2018
Drug	inhaled primatene will be given as a breathing treatment	1	2007
Diagnostic Test	initial breath volatile organic compounds	1	2018
Diagnostic Test	initial fecal microbiome	1	2018
Diagnostic Test	initial fecal volatile organic compounds	1	2018
Procedure	injection of onabotulinumtoxina (btx-a)	1	2018
Device	inpwt	1	2013
Dietary Supplement	intake of food product with a patented fermented rye bran	1	2016
Dietary Supplement	intake of food product with common refined wheat	1	2016
Behavioral	integrated management of infectious disease (imid)	1	2010
Device	integuseal	1	2009
Radiation	intensity-modulated radiation therapy (imrt)	1	2019
Behavioral	intensive education on personal hygiene	1	2007
Drug	interferon alfa-n3	1	1999
Drug	interferon gamma	1	1999
Drug	interferon gamma for aerosol	1	2001
Drug	interferon gamma, gm-csf	1	2005
Drug	interleukin-2 sa	1	2003
Other	interrupted suturing	1	2012
Other	interruption of antibiotic treatment due to pct measurement	1	2016
Procedure	intervention arm 1: covering with approved abdominal 3mâ„¢ steri-drapeâ„¢ wound edge protector intervention arm 2: covering with standard woven swabs	1	2010
Other	intervention cluster	1	2017
Other	intervention: education, decision support tools	1	2009
Biological	intestinal microbiota therapy	1	2014
Procedure	intra-peritoneal antibiotic lavage	1	2011
Procedure	intraoperative samples	1	2016
Drug	intraperitoneal daptomycin	1	2013
Drug	intravenous iclaprim	1	2006
Drug	intravenous iclaprim/intravenous linezolid	1	2006
Biological	intravenous injection of ebv specific ctls	1	2003
Drug	intravenous levonadifloxacin	1	2017
Drug	intravenous levonadifloxacin/linezolid infusion	1	2017
Drug	intravenous linezolid	1	2006
Dietary Supplement	inulin	1	2010
Drug	inulin oral suspension	1	2019
Drug	iodine	1	2013
Drug	iodophor (10% povidone-iodine)	1	2017
Device	iodophor antimicrobial incise drapes (drape)	1	2019
Procedure	ionic silver-containing dressing	1	2014
Drug	iramox	1	2016
Drug	iron	1	2006
Dietary Supplement	iron fumerate	1	2015
Device	irrisept system	1	2014
Drug	islatravir	1	2019
Other	isocaloric powder	1	2017
Drug	isolated 0.3% gatifloxacin	1	2010
Drug	isolated 0.3% gatifloxacin/1.0% prednisolone acetate	1	2010
Device	isolex 300i magnetic cell selector	1	1999
Drug	isoniazid/rifapentine	1	2012
Drug	isoniazid/rifapentine 12-weekly/pyridoxine (vitamin b6)	1	2018
Drug	isoniazid/rifapentine daily (4 weeks)/pyridoxine (vitamin b6)	1	2018
Biological	isopropyl alcohol	1	2011
Drug	isotonic saline.	1	2013
placebo	isotonic solution of sodium chloride (placebo)	1	2009
Drug	isotretinoin	1	1999
Other	its blankets.	1	2016
Drug	iv aztreonam	1	2007
Drug	iv dalbavancin	1	2011
Drug	iv gamunex 10%	1	2006
Drug	iv vancomycin/iv aztreonam	1	2007
Drug	ivermectin treatment	1	2005
Drug	ivig (privigen)	1	2014
Drug	jing fang bai du san	1	2009
Drug	jnj-32729463	1	2010
placebo	jnj-32729463 placebo	1	2010
Drug	jnj-53718678	1	2015
Drug	juc solution	1	2013
Drug	kaletra	1	2004
Drug	ketoconazole	1	1999
Drug	kg- 1 dose	1	2014
Drug	kg - 2 doses	1	2014
Drug	klacid	1	2016
Other	km	1	2019
Other	krp-ni	1	2019
Other	krp-ni / km	1	2019
Dietary Supplement	l-alanine	1	2012
Drug	l-methionine, hibiscus sabdariffa	1	2014
Drug	l-methionine, hibiscus sabdariffa/boswellia leaf extract	1	2014
Dietary Supplement	l reuteri in children on antibiotics	1	2011
Other	l reuteri pb-w1 strain	1	2017
Dietary Supplement	l. acidophilus dds-1, b. lactis uabla-12	1	2012
Other	l. reuteri dsm20016t strain	1	2017
Other	laboratory value procalcitonin	1	2008
Drug	lactin-v	1	2006
Dietary Supplement	lactobacillus fermentum	1	2010
Dietary Supplement	lactobacillus gg	1	2010
Dietary Supplement	lactobacillus helveticus r0052, bifidobacterium bifidum r0071, bifidobacterium infantis r0033	1	2008
Dietary Supplement	lactobacillus rhamnosus	1	2012
Other	lactobacillus rhamnosus bmx 54	1	2017
Dietary Supplement	lactolevure	1	2017
Drug	lactose	1	2018
Biological	laiv	1	2014
Drug	lamivudine-zidovudine (3tc-zdv)	1	2010
Drug	lamivudine (abc	1	2012
Drug	lamivudine (combivirâ®)	1	2006
Drug	lamivudine (or emtricitabine)	1	2009
Drug	lamivudine fdc	1	2013
Drug	lansoprazole, clarithromycin, amoxycillin	1	2007
Drug	lanzol	1	2016
Procedure	laparoscopic surgery	1	2014
Other	latent tuberculosis infection program evaluation	1	2016
Other	latent tuberculosis infection program evaluation/diagnosis	1	2016
Drug	ledipasvir	1	2015
Drug	ledipasvir/sofosbuvir	1	2015
Drug	letermovir iv	1	2019
Drug	letermovir pill	1	2019
Drug	letermovir tablet	1	2019
Procedure	leukocyte depletion of whole blood	1	2005
Other	leukocyte filtration	1	2005
Other	leukocyte filtration/depletion	1	2005
Drug	levocarnitine	1	1999
Drug	levofloxacin (oral)	1	2015
placebo	levofloxacin placebo	1	2014
Drug	levofloxacin quadruple regimen	1	2019
Drug	lff571	1	2010
Biological	lfmt	1	2017
Drug	liberase enzyme	1	2020
Other	linc-ii	1	2017
Drug	linezolid 600 mg	1	2018
Drug	linezolid infusion	1	2017
Drug	linezolid tablet	1	2017
Drug	liposomal amikacin for inhalation (arikayceâ„¢) using the pari investigational eflowâ® nebulizer.	1	2011
Drug	liposomal amphotericin b	1	1999
Other	liquid soap	1	2017
Drug	lithium	1	2011
Other	liver transplant	1	2016
Drug	lobucavir	1	1999
Drug	local application of collagen-gentamicin	1	2007
Other	longer therapy duration	1	2013
Drug	lopinavir-ritonavir (lpv-rtv)	1	2010
Drug	lopinavir 400 mg	1	2010
Drug	lopinavir 400 mg/ritonavir 100mg	1	2010
Drug	lopinavir/ ritonavir oral tablet	1	2020
Drug	lopinavir/ritonavir with two nucleoside analogs	1	2009
Biological	low	1	2020
Biological	low dose of h5 vlp vaccine	1	2013
Biological	low dose of h5 vlp vaccine / alhydrogel	1	2013
Biological	low dose of h5 vlp vaccine / gla-se	1	2013
Biological	low dose of h7 vlp vaccine	1	2013
Biological	low dose of h7 vlp vaccine / alhydrogel	1	2013
Other	low fiber diet	1	2019
Drug	low tacrolimus	1	2012
Biological	low/upper respiratory tract sample	1	2020
Biological	lsff	1	2017
Drug	ltx-109	1	2010
Procedure	lumbar puncture	1	2019
Drug	lumicitabine	1	2017
Procedure	lung function measurement	1	2015
Procedure	lymph node biospy	1	1999
Drug	macrolide treatment	1	2013
Drug	magnesium sulfate	1	1999
Procedure	magnetic resonance imaging	1	2015
Drug	magnex (sulbactam sodium	1	2006
Drug	magnex (sulbactam sodium/cefoperazone sodium 1:1) pfizer ltd.	1	2006
Other	mailing of antibiotic therapy guidelines to the sentinel physicians	1	2011
Drug	maintenance of the current regimen	1	2016
Other	malaria challenge infection, p. falciparum 3d7	1	2018
Device	malditof	1	2014
Behavioral	male sexual health program	1	2009
Dietary Supplement	maltodextrin	1	2015
Drug	mannose	1	2018
Procedure	manual bladder stimulation technique	1	2019
Drug	maribavir	1	1999
Device	mask, alcohol	1	2007
Device	mask, alcohol/hand sanitizer	1	2007
Procedure	mass closure	1	2007
Other	matched donor human milk	1	2019
placebo	matching placebo	1	2019
placebo	matching placebo to relebactam	1	2012
Biological	measles-mumps-rubella vaccine (live)	1	2001
Drug	mebendazole 2 x 500mg	1	2011
Drug	mebendazole 500mg	1	2011
Drug	mebendazole polymorph a	1	2011
Drug	mebendazole polymorph a/c 500 mg	1	2011
Drug	mebendazole polymorph c	1	2011
Biological	med dose of h5 vlp vaccine	1	2013
Biological	med dose of h5 vlp vaccine / alhydrogel	1	2013
Biological	med dose of h7 vlp vaccine	1	2013
Biological	med dose of h7 vlp vaccine / alhydrogel	1	2013
Biological	medi-524	1	2005
Biological	medi-534	1	2007
Drug	medi8897	1	2019
Behavioral	meditation	1	2010
Device	medixairâ®	1	2015
Drug	mefoxin 2g	1	2019
Biological	men c conjugate	1	2005
Biological	men c conjugate vaccine	1	2005
Biological	menjugate	1	2005
Biological	menjugate (meningococcal c conjugate vaccine)	1	2008
Device	menstrual cup	1	2017
Drug	meropenem intravenous	1	2014
Drug	meropenem/imipenem	1	2018
Drug	meropenem/saline placebo	1	2010
Drug	mesalamine (5-aminosalicylic acid, apriso)	1	2010
Drug	mesalazine 250mg	1	2018
Drug	mesalazine 250mg tablet	1	2018
Drug	mesalazine 250mg tablet/nitazoxanide 500mg oral tablet	1	2018
Drug	met-2	1	2016
Device	metal retractor	1	2016
Drug	metenkefalin	1	2020
Drug	metenkefalin / tridecactide	1	2020
Drug	metformin	1	2016
Drug	methenamine hippurate	1	2015
Drug	methotrexate	1	1999
Drug	metrogyl (metronidazole injection ip) j.b.chemicals	1	2006
Drug	metrogyl (metronidazole injection ip) j.b.chemicals/pharmaceuticals ltd.	1	2006
Drug	metronidazole 1 g intravenous	1	2015
Drug	metronidazole 250 mg oral	1	2015
Drug	metronidazole 500 mg	1	2016
Drug	metronidazole hydrochloride	1	2017
Drug	metronizadole	1	2005
Drug	mexiletine hydrochloride	1	1999
Biological	mf-59	1	2005
Biological	mf59	1	1999
Drug	micafungin (mycamine)	1	2008
Diagnostic Test	microbial culture	1	2018
Diagnostic Test	microbiome under chemotherapy	1	2018
Procedure	microdialysis	1	2008
Dietary Supplement	micronutrient powder (mnp)	1	2010
Dietary Supplement	micronutrients	1	2008
Dietary Supplement	micronutrients/antioxidants	1	2008
Drug	midazolam	1	2011
Dietary Supplement	miglyol oil	1	2010
Drug	mikacin (amikacin sulphate injection ip) aristo pharmaceuticals ltd.	1	2006
Other	mild intraoperative hypercapnia (50 mmhg vs. 30 mmhg)	1	2006
Procedure	mild soap skin cleanser	1	2013
Dietary Supplement	mineral water	1	2015
Dietary Supplement	minerals	1	2008
Biological	mirasol-treated fresh whole blood	1	2018
Biological	mk-3415	1	2010
Drug	mk-7655	1	2011
Drug	mk0518 (raltegravir)	1	2009
Drug	mk0826, ertapenem sodium / duration of treatment - 24 weeks	1	2005
Drug	mk0826, ertapenem sodium / duration of treatment: 14 days	1	2006
Drug	mk0826, ertapenem sodium /duration of treatment: 14 days	1	2007
Drug	mk0826; ertapenem sodium	1	2005
Drug	ml) im given once on day 1.	1	2015
Drug	mmh-407	1	2019
Biological	mn rgp120	1	1999
Biological	mn rgp120/hiv-1/gne8 rgp120/hiv-1	1	1999
Drug	modification for administration mode of cloxacillin antibiotic	1	2017
Drug	molgramostim nebulizer solution	1	2018
Device	mona lisa touch	1	2020
Drug	monotherapy (lopinavir	1	2009
Drug	monotherapy (lopinavir/ritonavir)	1	2009
Drug	monotherapy (lopinavir/ritonavir) / abc/3tc	1	2009
Biological	monovalent hbv vaccine	1	2017
Biological	monovalent live attenuated pandemic influenza vaccine	1	2009
Biological	montanide isa-51 adjuvant	1	2019
Drug	monthly antibiotic	1	2011
placebo	monthly placebo	1	2011
Procedure	mouth-rinse with 0.12% clorhexidine	1	2019
Procedure	mouth-rinse with isotonic solution with 1.5% sodium bicarbonate	1	2019
placebo	moxifloxacin placebo	1	2010
Diagnostic Test	mp diagnostics htlv blot 2.4	1	2017
Other	mr-proadm guided	1	2018
Diagnostic Test	mri	1	2019
Biological	mrkad5 hiv-1 gag	1	2005
Biological	mrkad5 hiv-1 gag/pol/nef	1	2005
Biological	mrkad5 hiv-1 gag/pol/nef placebo	1	2005
Biological	mrna-transfected autologous dendritic cells	1	2009
Drug	mrx-i	1	2014
Biological	mtp-pe	1	1999
Biological	mtp-pe/mf59	1	1999
Genetic	mucosal tissue sampling	1	2017
Dietary Supplement	multi-strain probiotic	1	2011
Biological	multi-virus specific t cells	1	2010
Behavioral	multimodal hygiene intervention	1	2018
Diagnostic Test	multiplex molecular diagnostic assay	1	2017
Biological	multivirus specific t cells	1	2014
Dietary Supplement	multivitamins	1	2008
Dietary Supplement	multivitamins/minerals	1	2008
Drug	mupirocin (bactroban) 2%; hexachlorophene (phisohex) 3%	1	2008
Drug	mupirocin (drug)	1	2006
Drug	mupirocin 2% nasal ointement	1	2015
Drug	mupirocin ointment [treatment]	1	2005
Procedure	mupirocin ointment application	1	2014
Drug	mupirocin, chlorhexidine,	1	2007
Drug	mupirocin, chlorhexidine,/household cleaning/disinfection	1	2007
Drug	mupirocin/chlorhexidine	1	2007
Biological	mva-b	1	2008
Biological	mva-nsmut	1	2014
Biological	mva.hivconsv	1	2014
Biological	mva.hpv16	1	2018
Biological	mva.hpv16/18	1	2018
Drug	mycophenolic acid	1	2014
Drug	mycophenolic acid dose reduction	1	2012
Drug	n-acetyl cysteine (nac)	1	2017
Drug	n-acetylcysteine	1	2006
Drug	n-acetylcysteine/placebo	1	2006
Biological	na-asp-2	1	2005
Biological	na-asp-2 skin test reagent	1	2009
Biological	na-asp-2/alhydrogel hookworm vaccine	1	2005
Biological	na-gst-1	1	2017
Biological	na-gst-1/alhydrogel	1	2017
Biological	na-gst-1/alhydrogel / cpg 10104	1	2017
Biological	na-gst-1/alhydrogel / gla-af	1	2017
Drug	nacl; saline	1	2018
Dietary Supplement	nanotechnology structured water magnalife	1	2020
Dietary Supplement	naringenin	1	2010
Drug	nasal antiseptic	1	2011
Drug	nasal mupirocin	1	2010
Drug	nasal povidone iodine	1	2014
Diagnostic Test	nasal swabs	1	2017
Other	nasal swabs for mrsa culture	1	2008
Other	nasal washing	1	2007
Diagnostic Test	naso-pharyngeal swab	1	2017
Diagnostic Test	naso-pharyngeal swab/sputum culture	1	2017
Other	nasopharyngeal swab sampling	1	2016
Procedure	nasopharyngeal washing for viral antigen detection by immunofluorescence initiated early in ed visit.	1	2006
Biological	navitoclax	1	2014
Biological	ndv-3 vaccine with alum im	1	2011
Biological	ndv-3 vaccine without alum id	1	2011
Biological	ndv-3 vaccine without alum im	1	2011
Drug	nebulizer.	1	2011
Biological	necator americanus hookworm larvae	1	2013
Biological	necator americanus l3 larvae	1	2017
Other	necator americanus larval inoculum	1	2017
Biological	nef	1	2005
placebo	nef placebo	1	2005
Biological	neftat	1	2005
Device	negative pressure pressure wound therapy	1	2019
Biological	neisseria gonorrhoeae strain fa1090 a26	1	2019
Biological	neisseria gonorrhoeae strain fa7537	1	2019
Biological	neisvacc (meningococcal c conjugate vaccine)	1	2008
Drug	nelfinavir	1	2005
Drug	neomycin	1	2017
Diagnostic Test	neumodx ct	1	2019
Diagnostic Test	neumodx ct/ng assay	1	2019
Drug	neutrolin	1	2016
Drug	nevirapine (nvp): antepartum mothers	1	2010
Drug	nevirapine (nvp): infant extended	1	2010
Drug	nevirapine (nvp): infant short-course	1	2010
Drug	nexium	1	2016
Drug	nexium 20 mg	1	2015
Drug	nexium 40 mg	1	2015
Diagnostic Test	ng assay	1	2019
Drug	nimorazole.	1	2019
Drug	nitazoxanide	1	2018
Drug	nitazoxanide (ntz)	1	2009
Drug	nitazoxanide with pegylated interferon	1	2010
Drug	nitazoxanide with pegylated interferon/ribavirin	1	2010
Drug	nitric oxide 0.5 %	1	2017
Drug	nitric oxide 0.5 % / nitrogen 99.5 % gas for inhalation	1	2017
Drug	nitrofurantoin 100 mg	1	2017
Drug	nitrofurantoin prophylaxis	1	2018
Drug	nitrofurantoin prophylaxis/placebo	1	2018
Drug	nitrogen 99.5 % gas for inhalation	1	2017
Drug	nitroglycerin-citrate-ethanol (nice)	1	2015
Biological	nk cells	1	2020
Drug	no antibiotics	1	2017
Behavioral	no feedback	1	2012
Other	no intervention - standard of care (soc) only	1	2014
Drug	no intervention; observational study	1	2005
Other	no treatment	1	2008
Device	no wound protector	1	2010
Biological	non-adjuvanted high dose of quadrivalent vlp vaccine	1	2014
Biological	non-adjuvanted low dose of quadrivalent vlp vaccine	1	2014
Biological	non-adjuvanted medium dose of quadrivalent vlp vaccine	1	2014
Other	non-chlorhexidine bathing	1	2014
Drug	non-coated suture	1	2018
Device	non-contact mce system	1	2020
Behavioral	non-impositive program for optimizing the use of antimicrobials	1	2019
Drug	non-quinolone antibiotic	1	2008
Procedure	non absorbable suture group	1	2012
Other	non fermented dairy product (control)	1	2009
Biological	non pulsed dendritic cell untreated patients	1	2006
Biological	non pulsed dendritic cell vaccine	1	2006
Other	none (control)	1	2019
Drug	nonoxynol-9	1	1999
Procedure	nopacking	1	2008
Other	normal maternity pads	1	2017
Other	normal saline irrigation	1	2012
Other	normal wound dressing	1	2017
Other	north american ginseng	1	2009
Other	not	1	2011
Device	not active	1	2015
Other	notification cards	1	2015
Other	nozinâ® nasal sanitizerâ®	1	2013
Device	nucleic acid amplification test	1	2005
Diagnostic Test	nucleic acid amplification test 1 for ng	1	2016
Diagnostic Test	nucleic acid amplification test 1 for ng/ct	1	2016
Diagnostic Test	nucleic acid amplification test 2 for ng	1	2016
Diagnostic Test	nucleic acid amplification test 2 for ng/ct	1	2016
Diagnostic Test	nucleic acid amplification test 3 for ng	1	2016
Diagnostic Test	nucleic acid amplification test 3 for ng/ct	1	2016
Other	nucleic acid amplification testing	1	2011
Behavioral	nudge using behavioral economic interventions	1	2018
Behavioral	nurse-led community health worker tbi (rn	1	2018
Behavioral	nurse-led community health worker tbi (rn/chw tbi) program	1	2018
Other	nurses informed	1	2018
Behavioral	nutrition training	1	2020
Procedure	nvhap prevention bundle	1	2017
Drug	nxl103	1	2009
Drug	nxl104	1	2008
Drug	nxl104 (q12h)	1	2011
Drug	nxl104 (q8h)	1	2011
Drug	nystatin oral	1	2017
Other	obemat2.0 therapy	1	2018
Other	observation	1	2010
Drug	obv	1	2014
Drug	obv/ptv/r	1	2014
Drug	ofloxacin	1	1999
Drug	ofloxacine	1	2015
Drug	ombitasvir, paritaprevir, ritonavir, dasabuvir	1	2015
Drug	omega-3 fatty acids (fish oil)	1	2012
Drug	omeprazole)	1	2008
Drug	omeprazole/amoxicillin	1	2009
Drug	omiganan 1% gel	1	2005
Dietary Supplement	omniplus supreme	1	2014
Procedure	on foley time	1	2007
Procedure	one-stage exchange joint replacement surgery	1	2016
Drug	one proton pump inhibitor, colloidal bismuth pectin	1	2018
Other	online disease surveillance data access	1	2010
Other	online tutorial	1	2016
Procedure	open colorectal surgery	1	2014
Procedure	open heart surgery	1	2016
Procedure	open hernia repair	1	2017
Drug	opioid based analgesia	1	2008
Device	opsite post-op visible standard sterile dressing	1	2018
Drug	optimized background regimen (obr)	1	2019
Other	option 1: national comparison	1	2019
Other	option 2: national comparison with benchmarking	1	2019
Diagnostic Test	optional blood testing per standard of care (aso, anti-strep, ana, anti-ds-dna, hla-b27, rf, lyme	1	2018
Diagnostic Test	optional blood testing per standard of care (aso, anti-strep, ana, anti-ds-dna, hla-b27, rf, lyme/other inflammatory/ rheumatologic markers )	1	2018
Other	optipac	1	2016
Drug	oral anti-mrsa antibiotic	1	2010
Drug	oral encochleated amphotericin b (camb)	1	2016
Drug	oral lenacapavir	1	2019
Drug	oral levonadifloxacin	1	2017
Drug	oral levonadifloxacin/linezolid tablet	1	2017
Drug	oral tablets	1	2006
Dietary Supplement	ordinary bottled drinking water	1	2020
Drug	oseltamivir	1	2008
Diagnostic Test	other inflammatory	1	2018
Drug	other medically-appropriate fda-approved antiretroviral therapy	1	2016
Behavioral	overdose education	1	2019
Drug	oxacillin	1	2002
Drug	oxantel pamoate	1	2017
Drug	oxygen	1	2016
Other	oxygen by mask	1	2009
Drug	p)	1	2019
Drug	p1101	1	2020
Drug	p1101 / ribavirin	1	2020
Drug	p128-0.1 mg	1	2012
Drug	p128-0.3 mg	1	2012
Drug	p128-1.0 mg	1	2012
Behavioral	p3 vaccine promotion package.	1	2012
Procedure	pacemaker pocket revision	1	2008
Behavioral	package of targeted interventions to reduce error	1	2006
Drug	paclitaxel	1	2006
Drug	paracetamol	1	2011
Diagnostic Test	parasitological diagnostics (coproscopy)	1	2018
Other	parent leaflet	1	2013
Other	parent survey	1	2016
Device	parentaral antimicrobials	1	2019
Device	parentaral antimicrobials/pure bone grafts	1	2019
Device	pari eflow nebulizer system	1	2018
Procedure	passive voiding trial	1	2016
Biological	pathogen-specific ctls	1	2017
Behavioral	patient-centered communication training	1	2005
Other	patient-centered monitoring	1	2017
Procedure	patient information leaflet (pil)	1	2014
Behavioral	patient safety health information technology	1	2016
Biological	patients treated by antibiotherapy	1	2018
Drug	pclus 3-18 mn	1	1999
Drug	pclus 6.1 mn	1	1999
Biological	pcv10	1	2018
Biological	pcv13	1	2018
Device	pds ii	1	2009
Device	pds plus	1	2009
Other	pea fiber bar	1	2019
Other	pears	1	2017
Behavioral	peer-led intervention (peer)	1	2017
Drug	peg	1	2013
Drug	peg-interferon a-2b	1	2005
Drug	peg-interferon a-2b / ribavirin	1	2005
Drug	peg-intron	1	2020
Drug	peg-intron / ribavirin	1	2020
Drug	pegasys (tm)	1	2014
Biological	pegfilgrastim	1	2006
Drug	pegifn-2b	1	2009
Drug	peginterferon	1	2009
Drug	peginterferon alfa-2b	1	2012
Drug	peginterferon alfa 2a	1	2008
Drug	pegylated interferon-alpha 2a, 180 mcg	1	2008
Drug	pegylated interferon-alpha 2a, 180 mcg/week sc	1	2008
Drug	pegylated interferon-alpha 2a, 90 mcg	1	2008
Drug	pegylated interferon-alpha 2a, 90 mcg/week sc	1	2008
Drug	pegylated interferon a-2a (peginf)	1	2013
Drug	pegylated interferon alfa-2a (peg)	1	2009
Drug	pegylated interferon alfa-2a (pegifnî±-2a)	1	2013
Drug	pegylated interferon alfa-2a / ribavirin	1	2009
Drug	pegylated interferon alpha 2-a (pegifn)	1	2013
Drug	pembrolizumab	1	2017
Drug	pentasa vs align	1	2018
Drug	pentoxifylline	1	1999
Biological	peptides on autologous dendritic cells	1	2009
Procedure	percutaneous isolated limb perfusion (pilp) delivery	1	2014
Other	performance feedback of the hh rates to hcws	1	2019
Drug	perineally immediately prior to surgery.	1	2019
Procedure	perineural catheterization implementation	1	2016
Procedure	perioperative supplemental oxygen	1	2005
Other	perioperative warming with forced air warming device	1	2016
Procedure	peripheral lymphocyte infusion	1	1999
Procedure	periprocedural antibiotics	1	2018
Procedure	perirectal swab sampling	1	2016
Drug	personal medication history guided therapy	1	2018
Other	pet scan	1	2009
Biological	pfspz-dvi challenge	1	2020
Drug	pharmaceuticals ltd.	1	2006
Behavioral	pharmacist-led intervention (pharm)	1	2017
Other	pharmacological study	1	2014
Drug	phenazopyridine hydrochloride tables, usp 200 mg	1	2012
Drug	phenoxymethylpenicillin	1	2019
Other	phone call	1	2020
Procedure	photodynamic treatment	1	2019
Other	physical assessment	1	2016
Drug	physiological saline	1	2018
Drug	pi	1	2016
Drug	pibrentasvir (g	1	2019
Drug	pibrentasvir 120 mg oral tablet	1	2019
Drug	piperacillin continuous infusion	1	2010
Drug	piperacillin extended infusion	1	2010
Drug	piperacillin sodium	1	2012
Drug	piperacillin sodium/sulbactam sodium	1	2012
Drug	piperacillin, tazobactam 4-0.5g solution for injection	1	2019
Drug	piperacillin/tazobactam-matching placebo	1	2011
Drug	piperacillin/tazobactam sodium	1	2011
Drug	piperacillin/tazobactam/amoxicillin/clavulanic acid	1	2006
Drug	piperaquine (high dose)	1	2018
Drug	piperaquine (low dose)	1	2018
placebo	placebo (liquid dosage form)	1	2017
placebo	placebo (saline for injection)	1	2019
placebo	placebo (saline solution)	1	2009
placebo	placebo beverage	1	2013
placebo	placebo capsule	1	2018
placebo	placebo cloth	1	2015
placebo	placebo comparator recombinant hepatitis b vaccine	1	2010
placebo	placebo comparator: placebo	1	2013
placebo	placebo comparator: placebo control	1	2009
placebo	placebo cranberry juice	1	2004
placebo	placebo cream	1	2012
placebo	placebo faecal transplantation	1	2019
placebo	placebo for abt-493	1	2015
Drug	placebo for abt-493/abt-530	1	2015
placebo	placebo for arabinoxylan rice bran	1	2016
placebo	placebo for metronidazole	1	2017
placebo	placebo gel	1	2003
placebo	placebo group	1	2008
placebo	placebo linezolid	1	2014
placebo	placebo matched to suptavumab	1	2014
placebo	placebo matching ribavirin tablet	1	2011
placebo	placebo matching tegobuvir capsule	1	2011
placebo	placebo matching with bms-955176	1	2013
placebo	placebo of ofloxacine	1	2015
placebo	placebo of phenazopyridine hydrochloride tables, usp 200 mg	1	2012
placebo	placebo ointment	1	2008
placebo	placebo oral suspension	1	2019
placebo	placebo powder capsules	1	2011
placebo	placebo tedizolid (bay119-2631)	1	2014
placebo	placebo to arctuvan	1	2017
placebo	placebo to boceprevir	1	2009
placebo	placebo to cms	1	2015
placebo	placebo to fosfomycin	1	2017
placebo	placebo to match gs-9857	1	2014
placebo	placebo to match ldv	1	2013
Drug	placebo to match ldv/sof	1	2013
placebo	placebo to match rbv	1	2013
placebo	placebo to metronidazole	1	2010
placebo	placebo to relebactam	1	2012
placebo	placebo with alum im	1	2011
placebo	placebo with no booster in stage 2	1	2009
Other	placebo/maxipim	1	2018
Drug	placebo/standard of care	1	2010
Other	plain soap	1	2009
Other	plain soap/water (psw)	1	2009
Other	plant based diet	1	2017
Biological	plasma	1	2020
Diagnostic Test	plasmatic ngal	1	2019
Diagnostic Test	plasmatic ngal/mri	1	2019
Procedure	pleural biopsy sampling	1	2015
Drug	pmx-30063-investigational drug	1	2010
Biological	pneumococcal conjugate 13 valent vaccine	1	2013
Biological	pneumococcal vaccine formulation 4	1	2011
Biological	pneumococcal vaccine formulation 5	1	2011
Biological	pneumococcal vaccine high dose (formulation 1)	1	2011
Biological	pneumococcal vaccine low dose (formulation 2)	1	2011
Biological	pneumococcal vaccine middle dose (formulation 3)	1	2011
Biological	pneumococcal vaccine middle dose (formulation 4)	1	2011
Biological	pneumovax	1	2006
Diagnostic Test	point of care early infant diagnosis	1	2019
Biological	pol	1	2005
Drug	polihexanide; serasept	1	2018
Drug	poly-iclc	1	2010
Drug	polyethylene glycol	1	2017
placebo	polyethylene glycol ointment [placebo]	1	2005
Drug	polyethylene glycol solution for daily bowel lavage.	1	2012
Drug	posaconazole 200 mg	1	2013
Drug	posaconazole 300 mg	1	2013
Behavioral	positive deviance	1	2014
Other	postoperative early shower	1	2020
Drug	povidine-iodine	1	2018
Drug	povidon iodine	1	2016
Procedure	povidone	1	2012
Drug	povidone-iodine 10%	1	2005
Other	povidone iodine	1	2014
Drug	povidone iodine 1% solution	1	2018
Drug	povidone iodine 10% vand cesarean section wound infections	1	2012
Drug	povidone iodine 7.5% vand cesarean section wound infections	1	2012
Drug	povidone/iodine	1	2006
Drug	pp4001	1	2011
Drug	praziquantel	1	2007
Dietary Supplement	prebiotic inulin-type fructan	1	2017
Dietary Supplement	prebiotic inulin-type fructans	1	2018
Drug	premarin vaginal cream	1	2012
Other	preparing skin’s areas to be tested	1	2011
Other	preparing skin’s areas to be tested with two antiseptics	1	2013
Other	preparing skin’s areas to be tested with two antiseptics/two controls	1	2013
placebo	presatovir placebo	1	2014
Other	preterm infant formula	1	2017
Device	prevana dressing	1	2015
Device	prevena	1	2018
Device	prevena dressing	1	2015
Device	prevena negative pressure wound system	1	2012
Device	prevenaâ„¢ ims	1	2015
Device	prevenaâ„¢ incision management system (pims)	1	2011
Biological	prevenar13	1	2012
Procedure	prevention	1	2020
Drug	preventive treatment with isoniazid	1	2010
Drug	preventive treatment with isoniazid.	1	2010
Biological	prevnar	1	2006
Biological	prevnar-13	1	2018
Biological	prevnar 13â®	1	2014
Other	prewarming	1	2016
Other	prewarming/perioperative warming with forced air warming device/its blankets.	1	2016
Drug	primaquine	1	2014
Procedure	primary closure	1	2015
Procedure	primary wound closure	1	2012
Behavioral	prioritizing needs (5 minutes)	1	2017
Drug	pritelivir	1	2017
Drug	pro 140	1	2008
Drug	pro 140 (humanized monoclonal antibody to ccr5)	1	2008
Drug	pro 2000/5	1	2005
Drug	pro 2000/5 gel	1	2003
Drug	probenecid	1	2017
Dietary Supplement	probi defendum	1	2015
Dietary Supplement	probiotic (2 * 10^9 cfu	1	2014
Dietary Supplement	probiotic (2 * 10^9 cfu/day)	1	2014
Dietary Supplement	probiotic capsule gr-1	1	2018
Dietary Supplement	probiotic capsule gr-1/rc-14	1	2018
Dietary Supplement	probiotics lactobacillus acidophilus boucardii	1	2014
Dietary Supplement	probiotics product	1	2020
Biological	procalcitonin dosages	1	2012
Procedure	procalcitonin guided antibiotic therapy	1	2004
Behavioral	procter	1	2010
Behavioral	procter/gamble school-based handwashing promotion program	1	2010
Behavioral	progressive resistance exercise training	1	2007
Behavioral	prolonged mechanical ventilation	1	2006
Drug	propan-2-ol	1	2013
Drug	prophylaxis of opportunistic infections	1	2007
Drug	prophylaxis of opportunistic infections/support treatment	1	2007
Drug	propofol	1	2020
Device	prospective tdm arm of colistin	1	2013
Device	protapernext x3 gutta-percha	1	2018
Drug	provodine	1	2015
Drug	prulifloxacin	1	2014
placebo	prulifloxacin placebo	1	2014
Behavioral	psycho-educational content (5 minutes)	1	2017
Drug	ptv	1	2014
Biological	pulsed dendritic cell vaccine	1	2006
Device	pulsed uv device	1	2017
Device	pure bone grafts	1	2019
Biological	pyo phage	1	2017
Drug	pyrantel-oxantel	1	2011
Drug	pyrantel-oxantel / mebendazole	1	2011
Drug	pyrantel pamoate	1	2017
Drug	pyridoxine (vitamin b6)	1	2018
Drug	pyrimethamine	1	1999
Drug	pz-601	1	2008
Biological	quadrivalent comparator vaccine	1	2018
Biological	quadrivalent hpv vaccine	1	2014
Biological	quadrivalent vlp influenza vaccine	1	2017
Combination Product	quadruple therapy	1	2019
Other	quality of life questionary	1	2016
Other	quaternary ammonium	1	2012
Other	quaternary ammonium/uv-c light	1	2012
Drug	r-chop	1	2007
Behavioral	r - autodialers	1	2017
Behavioral	r - mailed postcard	1	2017
Behavioral	r - texting	1	2017
Drug	r monotherapy (kaletra)	1	2009
Drug	r)	1	2007
Behavioral	r/r - autodialers	1	2017
Behavioral	r/r - mailed postcard	1	2017
Behavioral	r/r - texting	1	2017
Drug	rabeprazole	1	2015
Drug	rabeprazole-based triple therapy	1	2015
Drug	rabeprazole sodium	1	2005
Drug	rabeprazole, metronidazole, clarithromycin, amoxicillin	1	2010
Drug	rabeprazole/3 antibiotics	1	2015
Drug	rabeprazole/amox/tetr/levo	1	2015
Drug	rabeprazole/bismuth/2 antibiotics	1	2015
Drug	radezolid	1	2008
Drug	raltegravir (isentress)	1	2010
placebo	raltegravir placebo	1	2010
Drug	raltegravir qd	1	2009
Drug	raltegravir.	1	2008
Drug	raltegravir; maraviroc; darunavir; ritonavir; tenofovir	1	2009
Drug	raltegravir; maraviroc; darunavir; ritonavir; tenofovir/emtricitabine	1	2009
Diagnostic Test	rapid diagnostics alone	1	2017
Other	rapid molecular mrsa test	1	2008
Device	rapid respiratory pathogen nucleic acid amplification test	1	2016
Drug	ravuconazole	1	2003
Biological	rbx7455	1	2016
Dietary Supplement	rc-14	1	2018
Behavioral	re-entry health linkage	1	2019
Behavioral	readiness assessment (10 minutes)	1	2017
Dietary Supplement	ready to use therapeutic food (rutf)	1	2010
Other	real-time antimicrobial stewardship decision support	1	2017
Biological	recombinant human papillomavirus nonavalent vaccine	1	2017
Biological	recombinant interferon gamma	1	2003
Drug	reconvan, dipeptiven, omegaven	1	2008
Procedure	rectal swab	1	2019
Other	reduced number of pills	1	2009
Drug	rel	1	2019
Drug	rel fdc	1	2017
Other	release of test results	1	2013
Behavioral	reminders	1	2018
Procedure	removal of infected implant	1	2017
Drug	rep 2139-ca	1	2014
Drug	rep 2139-ca / pegasys (tm)	1	2014
Other	rephresh pro-b	1	2019
Procedure	respiratory bundle	1	2020
Procedure	respiratory bundle/prevention	1	2020
Biological	respiratory tract sample	1	2020
Drug	retapamulin (altabax)	1	2010
Drug	retapamulin ointment, 1%	1	2007
Other	retrospective examination by experts whether care given fo child admitted at the icu for suspicion of bacterial infection (not nosocomial) was optimal	1	2011
Other	retrospective examination by experts whether care given fo child admitted at the icu for suspicion of bacterial infection (not nosocomial) was optimal/not	1	2011
Drug	reverse hybrid regimen	1	2019
Drug	reverse hybrid therapy	1	2015
Drug	rezafungin for injection	1	2020
Biological	rgp120	1	1999
Biological	rgp120/hiv-1 sf-2	1	1999
Biological	rgp120/hiv-1mn	1	1999
Diagnostic Test	rheumatologic markers )	1	2018
Biological	ri-001	1	2008
Drug	ribavirin tablet	1	2011
Other	riboflavin	1	2012
Drug	rifabutin in combination with efavirenz	1	2008
Drug	rifabutin in combination with lopinavir	1	2008
Drug	rifabutin in combination with lopinavir boosted by ritonavir - dosing schedule 1	1	2008
Drug	rifabutin in combination with lopinavir boosted by ritonavir - dosing schedule 2	1	2008
Drug	rifabutin in combination with lopinavir/ritonavir	1	2008
Drug	rifabutin in combination with nevirapine	1	2008
Drug	rifalazil 25 milligram	1	2012
Biological	rifampicin dosages	1	2016
Drug	rifapentine 12-weekly	1	2018
Drug	rifapentine daily (4 weeks)	1	2018
Drug	rilpivirine	1	2007
Drug	rilpivirine - injectable suspension (rpv la)	1	2016
Drug	rilpivirine (rpv) tablet	1	2016
Drug	ritonavir (	1	2007
Drug	ritonavir 100mg	1	2010
Drug	ritonavir oral tablet	1	2020
Drug	ritonavir oral tablets	1	2020
Drug	ritonavir with two nucleoside analogs	1	2009
Drug	ritonavir, abt-267	1	2012
Drug	rivaroxaban, 10 mg	1	2014
Drug	rivaroxaban, 7.5 mg	1	2014
Drug	rivastigmine	1	2011
Drug	ro 24-7429	1	1999
Drug	ro7079901	1	2017
Drug	ro7239958	1	2018
Biological	rotateq	1	2009
Other	routine clinical microbiology	1	2014
Drug	rpv fdc	1	2016
Biological	rsv a memphis 37	1	2011
Biological	rsv a2	1	2017
Drug	rsv polyclonal immunoglobulin	1	1999
Drug	rtv	1	2019
Biological	ruti	1	2010
placebo	ruti matching placebo	1	2010
Drug	ruzasvir	1	2014
Drug	rv521 oral tablet	1	2020
Drug	s-649266	1	2016
Drug	s. aureus	1	2014
placebo	sa3ag followed by placebo	1	2009
Biological	sa3ag vaccine	1	2009
Biological	sa3ag with no booster in stage 2	1	2009
Dietary Supplement	sachet with cranberry	1	2017
Dietary Supplement	sachet with cranberry / placebo	1	2017
Drug	saline 0.9%	1	2014
Procedure	saline lavage	1	2010
Procedure	saliva swab	1	2010
Biological	salmonella typhi challenge	1	2019
Drug	salvage treatment for failed eradication	1	2018
Genetic	sb-728-t	1	2010
Drug	sb9200	1	2013
Behavioral	school-based sexuality	1	2019
Behavioral	school-based sexuality/hiv prevention scripted lesson plans	1	2019
Other	screen-and-treat	1	2013
Other	screen of crkp	1	2020
Other	screen of crkp/infection control measure	1	2020
Behavioral	script	1	2015
Drug	scrt	1	2009
Drug	sdz msl-109	1	2000
Dietary Supplement	selenium	1	2005
Procedure	self-collected vaginal swab for chlamydia testing	1	2005
Behavioral	self administered therapy (sat)	1	2012
Drug	selinexor	1	2020
Drug	semi-synthetic penicillins (ssps)	1	2010
Procedure	sequenced bilateral tka	1	2020
Diagnostic Test	serum c-reactive protein (crp)	1	2018
Diagnostic Test	serum cell count	1	2018
Diagnostic Test	serum cell count / differential (cbc)	1	2018
Diagnostic Test	serum d-dimer	1	2018
Diagnostic Test	serum erythrocyte sedimentation rate (esr)	1	2018
Diagnostic Test	serum procalcitonin	1	2018
Behavioral	session wrap (5 minutes)	1	2017
Drug	sevirumab	1	1999
Drug	sevoflurane	1	2020
Drug	sh229	1	2018
Device	sham device	1	2017
Device	sharklet catheter insertion	1	2016
Other	short pap	1	2017
Drug	short treatment (ciprofloxacin)	1	2008
Other	shortened course of antibiotic therapy	1	2008
Other	shorter therapy duration	1	2013
Drug	sildenafil	1	2013
Device	silicone foley catheter insertion	1	2016
Device	silicone urinary catheter	1	2010
Device	silver doped hydroxyapatite coated implants	1	2017
Drug	silver nanoparticles	1	2018
Device	silver spc	1	2011
Other	silverlon	1	2010
Behavioral	simple reminder	1	2015
Procedure	simultaneous bilateral total knee arthroplasty	1	2020
Drug	single arm (ganciclovir	1	2008
Drug	single arm (ganciclovir/valganciclovir)	1	2008
Drug	sitafloxacin	1	2016
Drug	site-specific empiric regimens included: meropenem	1	2007
Behavioral	skin intervention	1	2013
Drug	skin prep benzoyl peroxide	1	2015
Drug	skin prep chlorhexidine	1	2015
Procedure	small stitches	1	2007
Diagnostic Test	smart catheter biosensor	1	2020
Behavioral	smart form	1	2005
Behavioral	sms reminders	1	2012
Drug	smx)	1	2020
Other	smz prophylaxis	1	2011
Behavioral	social media	1	2013
Behavioral	social media/information pages	1	2013
Other	sodium chloride	1	2014
Drug	sodium mycophenolate	1	2012
Drug	sof/gs-5816	1	2014
Drug	sofosbuvir, ribavirin,	1	2014
Drug	sofosbuvir, ribavirin,/stribild	1	2014
Drug	sofosbuvir/daclatasvir	1	2015
Drug	sorafenib	1	2014
Drug	sorafenib tosylate	1	2014
Dietary Supplement	sorbitol	1	2008
Device	speedicath	1	2006
Biological	split-virion, non-adjuvanted h1n1 vaccine of 15 î¼g	1	2013
Biological	split-virion, non-adjuvanted h1n1 vaccine of 30 î¼g	1	2009
Biological	split, inactivated, trivalent influenza vaccine ( fluzoneâ® 2006	1	2006
Biological	split, inactivated, trivalent influenza vaccine ( fluzoneâ® 2006/2007 formulation)	1	2006
Device	sponges (sponge)	1	2019
Dietary Supplement	sprinkles	1	2006
Diagnostic Test	sputum culture	1	2017
Drug	sq ivig	1	2011
Other	ssi screening tool used in home visits by chws	1	2017
Other	ssi screening tool used via phone call follow-up	1	2017
Drug	standard	1	2016
Device	standard-of-care dressing	1	2011
Other	standard-of-care infection control approach	1	2014
Other	standard antibiotic stewardship	1	2017
Drug	standard antibiotic therapy	1	2014
Drug	standard antimicrobial therapy	1	2008
Other	standard bathing	1	2012
Behavioral	standard counseling	1	2010
Drug	standard dose vitamin d	1	2010
Other	standard dry gauze dressing	1	2015
Other	standard formula	1	2020
Biological	standard fresh whole blood	1	2018
Drug	standard glycemic	1	2013
Other	standard hospital care	1	2015
Other	standard of care - chlorhexidine scrub only	1	2014
Drug	standard of care antibiotics	1	2015
Procedure	standard of care catheter insertion	1	2017
Drug	standard of care combinational antiretroviral therapy	1	2015
Diagnostic Test	standard of care early infant diagnosis	1	2019
Procedure	standard operating management	1	2009
Procedure	standard oxygen	1	2005
Other	standard postoperative wound dressing	1	2013
Behavioral	standard practices to reduce health system antibiotic prescription	1	2018
Procedure	standard proctologic examination	1	2014
Other	standard soap	1	2018
Device	standard spc	1	2011
Device	standard surgical dressing	1	2014
Other	standard surgical retractors	1	2015
Other	standard treatment without homeopathy	1	2011
Drug	standard triple therapy	1	2015
Dietary Supplement	starch of potato	1	2008
Other	starter infant formula with pro	1	2013
Other	starter infant formula with pro/prebiotics	1	2013
Procedure	static spacer	1	2011
Other	sterile bacteriology media	1	2017
Procedure	sterile patient preparation for cystoscopy	1	2005
Other	sterile plaster dressings	1	2015
Other	sterile water	1	2018
Drug	steroids	1	2012
Device	stimulan rapid cure	1	2017
Procedure	stool	1	2016
Biological	stool collection	1	2020
Other	stool sample collection	1	2012
Procedure	stool/perirectal swab sampling	1	2016
Biological	strain of the licensed quadrivalent vaccine	1	2016
Biological	strain)	1	2016
Other	strawberry fruit pieces	1	2010
Drug	stribild	1	2014
Other	strip peri screen	1	2014
Drug	structured treatment interruptions	1	2006
Drug	study group	1	2018
Behavioral	style brazil	1	2013
Drug	subcutaneous lenacapavir	1	2019
Other	subcuticular suturing	1	2012
Procedure	subinguinal microscopic varicocelectomy	1	2017
Device	suction	1	2013
Drug	sulbactam-etx2514	1	2018
Drug	sulbactam sodium	1	2012
Drug	sulbactam sodium for injection	1	2019
Drug	sulfa ds	1	2009
Drug	sulfadoxine-pyrimethamine (fansidar)	1	2005
Drug	sulfadoxine pyrimethamine	1	2018
Drug	sulfamethoxazole trimethoprim	1	2013
Drug	sulopenem-etzadroxil	1	2017
Drug	sulopenem-etzadroxil/probenecid	1	2017
Behavioral	supervision	1	2010
Other	supplemental oxygen (80% vs. 30%)	1	2006
Device	supplemental oxygen 80% fio2	1	2011
Other	supplemental training, education	1	2010
Other	supplemental training, education/hygiene	1	2010
Other	supplemented formula	1	2020
Drug	support treatment	1	2007
Device	supporting life electronic community case management	1	2016
Drug	suptavumab 30 mg	1	2014
Drug	suptavumab 30 mg/kg	1	2014
Drug	suptavumab 30 mg/kg- 1 dose	1	2014
Drug	suptavumab 30 mg/kg - 2 doses	1	2014
Device	surgery alone	1	2015
Drug	susceptibility guided therapy	1	2018
Drug	susceptibility test guided sequential therapy	1	2009
Biological	swab	1	2020
Other	sweet potatos	1	2017
Other	sweetened, dried cranberries	1	2010
Drug	switch to dtg	1	2017
Drug	switch to dtg / ftc	1	2017
Drug	switching to lpv	1	2009
Drug	switching to lpv/r monotherapy (kaletra)	1	2009
Drug	symbicort	1	2020
Behavioral	symptom diary	1	2015
Combination Product	symtuza	1	2019
Combination Product	symtuza/dolutegravir	1	2019
Biological	synflorix	1	2012
Biological	synflorixâ„¢	1	2012
Diagnostic Test	synovial alpha-defensin assay	1	2018
Diagnostic Test	synovial bacterial culture by bact	1	2018
Diagnostic Test	synovial bacterial culture by bact/alert	1	2018
Diagnostic Test	synovial c-reactive protein (crp)	1	2018
Diagnostic Test	synovial candida spp antigen panel	1	2018
Diagnostic Test	synovial cell count	1	2018
Diagnostic Test	synovial cell count / differential (cbc)	1	2018
Diagnostic Test	synovial enterococcus faecalis assay	1	2018
Diagnostic Test	synovial gram stain	1	2018
Diagnostic Test	synovial lactate assay	1	2018
Diagnostic Test	synovial leukocyte esterase test strips	1	2018
Diagnostic Test	synovial neutrophil elastase assay	1	2018
Diagnostic Test	synovial pcr for kingella kingae	1	2018
Diagnostic Test	synovial staphylococcus spp antigen panel	1	2018
Biological	t cell vaccination	1	2006
Drug	t3 solution	1	2020
Drug	tablet cefixime	1	2018
Drug	tablet cefuroxime	1	2018
Drug	tablet ciprofloxacin	1	2018
Drug	tablet ciprofloxacin/ tablet cefixime/ tablet cefuroxime	1	2018
Drug	tablet nitrofurantoin	1	2018
placebo	taf placebo	1	2016
Behavioral	tailored	1	2016
Behavioral	tailored oral health literacy instruction	1	2010
Diagnostic Test	target enriched multiplex pcr (tem- pcr)	1	2018
Behavioral	targeted infection control	1	2010
Drug	tavanex	1	2016
placebo	tazobactam-matching placebo	1	2011
Drug	tazobactam 1000	1	2014
Drug	tazobactam 12	1	2014
Drug	tazobactam 18	1	2014
Drug	tazobactam 20	1	2014
Drug	tazobactam 30	1	2014
Drug	tazobactam sodium	1	2011
Other	tb infection-screening benefiting group	1	2020
Drug	td-1607	1	2013
Drug	td-1792	1	2007
Drug	tdf treatment	1	2011
Drug	tdf)	1	2007
Drug	tdf/3tc/efv / telmisartan	1	2015
Drug	tdf/3tc/efv only	1	2015
Behavioral	teach-pd training curriculum	1	2018
Drug	tebipenem pivoxil hydrobromide (tbpm-pi-hbr)	1	2018
Drug	tedizolid (bay119-2631)	1	2014
Drug	tedizolid phophate	1	2014
Drug	tedizolid phosphate	1	2017
Drug	tedizolid phosphate (sivextro, bay1192631)	1	2013
Drug	tedizolid phosphate 200 mg [sivextro]	1	2017
Procedure	tegaderm, tegaderm hp, tegaderm chg	1	2010
Drug	tegobuvir capsule	1	2011
Drug	telbivudine	1	2013
Drug	telithromycin (hmr3647)	1	2006
Drug	tenofovir / emtricitabine / raltegravir.	1	2008
Drug	tenofovir 300mg	1	2010
Drug	tenofovir alafenamid fumarate	1	2007
Drug	tenofovir alafenamide	1	2016
Drug	tenofovir disoproxil	1	2015
Drug	tenofovir disoproxil fumarate (ftc	1	2007
Drug	tenofovir disoproxil fumarate (tdf) 300 mg oral daily.	1	2018
Drug	tenofovir disoproxil fumarate (tdf)/lamivudine (3tc)	1	2018
Drug	tenofovir disoproxil fumarate/emtricitabine	1	2006
Drug	tenofovir disoproxil once daily	1	2008
Drug	tenofovir disoproxil twice daily	1	2008
Drug	tenofovir/emtricitabine fdc	1	2013
Drug	tenofovir/emtricitabine/efavirenz	1	2007
Biological	tetanus toxoids	1	2001
Drug	tetr	1	2015
Drug	tetra	1	2015
Drug	tetracycline)	1	2018
Drug	tg-873870 (nemonoxacin)	1	2008
Biological	tgaac09	1	2009
Other	theo	1	2015
Procedure	therapeutic conventional surgery	1	2017
Other	theraworx bath wipes	1	2018
Drug	thymoglobulin	1	2012
Drug	tight glycemic	1	2013
Behavioral	time, attention,	1	2019
Behavioral	time, attention,/information-matched control	1	2019
Drug	timentin	1	2014
Drug	tinafas	1	2016
Drug	tipranavir	1	2005
Drug	tipranavir/ritonavir	1	2005
Other	tissue analysis	1	2015
Drug	tissue plasminogen activator (tpa)	1	2018
Drug	tissue plasminogen activator (tpa)/human recombinant deoxyribonuclease (dnase)	1	2018
Drug	tissue sampling (lung)	1	2018
Drug	tmc278 la	1	2014
Drug	tmc435	1	2013
Drug	tmp-smx	1	2018
Drug	tnp-2092	1	2019
Drug	tobramycin	1	2017
Drug	tobramycin inhalation solution using a pari lcâ®	1	2011
Drug	tobramycin inhalation solution using a pari lcâ®/nebulizer.	1	2011
Drug	tocilizumab	1	2014
Drug	topical 3% hexachlorophene body wash	1	2010
Drug	topical anti-infective product	1	2017
Drug	topical approved anti-microbial gel	1	2018
Drug	topical ointment	1	2017
Drug	tp-434	1	2010
Drug	tr-701 200 mg	1	2008
Drug	tr-701 300 mg	1	2008
Drug	tr-701 400 mg	1	2008
Device	tracoe cuff pressure controller	1	2016
Drug	tradipitant	1	2020
Procedure	traditional chinese acupuncture	1	2007
Behavioral	training	1	2010
Behavioral	training/supervision	1	2010
Dietary Supplement	transfer factor	1	2010
Procedure	transoral robotic surgery (tors) with neck dissection	1	2019
Other	treatment as usual	1	2013
Drug	treatment with anti-sti	1	2008
Drug	treatment with anti-sti/anti-schistosoma regimens	1	2008
Drug	tridecactide	1	2020
Drug	trifluridine	1	1999
Drug	trim	1	2009
Drug	trim/ sulfa ds	1	2009
Drug	trimethoprim-sulfamethoxazole (tmp	1	2020
Drug	trimethoprim-sulfamethoxazole (tmp-smx)	1	2008
Drug	trimethoprim-sulfamethoxazole (tmp/smx)	1	2020
Drug	trimethoprim-sulfamethoxazole / metronidazole	1	2008
Drug	trimethoprim-sulfamethoxazole/doxycycline	1	2007
Drug	trimethoprim / sulfamethoxazole	1	2017
Drug	triptolide wilfordii	1	2018
placebo	tris buffered saline (placebo)	1	2011
Biological	trivalent inactivated influenza vaccine	1	2005
Biological	trivalent live attenuated seasonal influenza vaccine	1	2009
Biological	trivirus specific ctls for ebv, cmv	1	2008
Biological	trivirus specific ctls for ebv, cmv/adenovirus infection	1	2008
Drug	trizivir	1	2004
Drug	truvadaâ®	1	2010
Procedure	tsvf	1	2020
Drug	tuberculin purified protein derivative	1	1999
Procedure	two-stage exchange joint replacement surgery	1	2016
Drug	two antibiotics based on personal medication history(amoxicillin,levofloxacin, furazolidone)	1	2018
Other	two controls	1	2013
Diagnostic Test	two samples on each of the three sites (pharynx, rectum, urine)	1	2018
Drug	two sensitive antibiotics(amoxicillin, clarithromycin, metronidazole, tinidazole, levofloxacin, furazolidone	1	2018
Drug	two sensitive antibiotics(amoxicillin, clarithromycin, metronidazole, tinidazole, levofloxacin, furazolidone/tetracycline)	1	2018
Drug	tygacil	1	2007
Biological	typhoid vi polysaccharide	1	2012
Device	tyrxâ„¢ absorbable antibacterial envelope	1	2014
Diagnostic Test	ultrapro	1	2017
Procedure	ultrashort heat inactivation	1	2010
Other	ultraviolet-a	1	2012
Other	ultraviolet-a/riboflavin	1	2012
Device	umbilical catheterization (agion )	1	2012
Device	umbilical catheterization (argyletm)	1	2012
Drug	universal antibiotic prophylaxis	1	2013
Behavioral	untailored	1	2016
Biological	upper respiratory sample	1	2020
Device	urinary catheterization	1	2019
Procedure	urine collection	1	2012
Procedure	urine sampling	1	2010
Procedure	use of air (no oxygen during surgery)	1	2011
Device	use of c-reactive protein (crp) point of care test	1	2013
Procedure	use of creatine monohydrate (a dietary supplement)	1	2007
Device	use of plastic ring wound retractor	1	2017
Drug	usual antibiotics (cloxacillin, cefazolin, daptomycin)	1	2019
Other	usual clinical practice	1	2018
Drug	usual practice / symbicort rapihaler	1	2020
Other	uv-c light	1	2012
Biological	v114 0.5x:0.5x:2x	1	2014
Biological	v114 1x:1x:1x	1	2014
Biological	v114 1x:1x:2x	1	2014
Biological	v114 2x:1x:2x	1	2014
Biological	v114 2x:2x:2x	1	2014
Biological	vaccination	1	2017
Biological	vaccination pneumovax 23	1	2014
Biological	vaccination ppv23	1	2014
Biological	vaccinations on day 0, day 28,	1	2018
Biological	vaccinations on day 0, day 28,/day 140	1	2018
Behavioral	vaccine information pages	1	2013
Procedure	vacuum assisted closure	1	2015
Procedure	vaginal preparation	1	2019
Other	vaginal sampling	1	2016
Drug	vaginal scrub, to be applied vaginally	1	2019
Drug	vaginal scrub, to be applied vaginally/perineally immediately prior to surgery.	1	2019
Procedure	vaginal self-sampling	1	2019
Procedure	vaginal swab	1	2010
Other	vagino-perineal swab	1	2014
Drug	vagitrol v	1	2013
Drug	valacyclovir arrow	1	2012
Drug	valacyclovir oral solution	1	2012
Drug	valacyclovir tablet	1	2012
Drug	valganciclovir)	1	2008
Drug	valomaciclovir	1	2007
Drug	vancomycin (before randomization)	1	2014
Drug	vancomycin (poc)	1	2010
Drug	vancomycin / linezolid	1	2011
Drug	vancomycin //- aztreonam/cefazolin //- aztreonam	1	2011
Drug	vancomycin antibiotic powder	1	2014
Drug	vancomycin iv	1	2015
Drug	vancomycin with aztreonam	1	2005
Drug	vancomycin/ceftazidime	1	2005
Drug	vancomycin/linezolid	1	2011
Drug	vancomycin/semi-synthetic penicillins (ssps)	1	2010
Biological	vaxem hib (haemophilus influenzae type b (hib) vaccine)	1	2009
Drug	vch 916	1	2008
Drug	vdv	1	2014
Device	vdw ultra	1	2018
Drug	ve303	1	2018
Biological	vedolizumab (brand name entyvio)	1	2017
Procedure	venovenous hemofiltration	1	2006
Drug	veronate	1	2005
Drug	very low tacrolimus	1	2012
Drug	vfend - voriconazole	1	2006
Drug	vfendâ®(voriconazole) iv 200mg	1	2015
Drug	vibramycin (doxycyline hyclate) capsule	1	2010
Drug	vicryl-plus, monocryl-plus, pds-plus (triclosan-coated sutures)	1	2017
Other	vicryl, monocryl, pds (not coated with triclosan)	1	2017
Device	vicrylâ®	1	2016
Device	vicrylplusâ®	1	2016
Drug	vidarabine	1	1999
Device	vidas b.r.a.h.m.s procalcitonin test (pct)	1	2017
Drug	vigamox (moxifloxacin hydrochloride ophthalmic solution)	1	2007
Drug	vigamox eye drops	1	2007
Dietary Supplement	vigantol oil)	1	2010
Biological	viral specific ctl infusion	1	2015
Biological	viral specific t-cells (vsts)	1	2019
Biological	virus specific t-cell (vst) infusion	1	2018
Biological	virus specific t cells (vsts)	1	2017
Other	visible light only	1	2012
Other	visualization tool	1	2018
Dietary Supplement	vitamin d supplement	1	2007
Dietary Supplement	vitamin d supplements	1	2012
placebo	vitamin d3 placebo	1	2012
Dietary Supplement	vitamin d3 supplementation	1	2013
Dietary Supplement	vitamins	1	2020
placebo	viusid placebo	1	2018
Dietary Supplement	viusidâ®	1	2018
Drug	vm-1500	1	2015
Drug	vm-1500/placebo	1	2015
Drug	vnrx-5133 (taniborbactam)	1	2019
Drug	vonoprazan	1	2019
Drug	vorico injection 200mg(voriconazole)	1	2015
Combination Product	vp-102	1	2019
Drug	vp-102-cantharidin topical film forming solution	1	2018
Device	vp-102 applicator	1	2018
Combination Product	vp-102/applicator	1	2019
Biological	vp20621	1	2010
Biological	vpm1002	1	2020
Biological	vrc-hivdna009-00-vp	1	2005
Other	vrc-pbspla043-00-vp	1	2017
Biological	vrc-zkadna090-00-vp	1	2017
Other	washcloths impregnated with 2% chlorhexidine gluconate	1	2015
Other	water	1	2008
Other	water (psw)	1	2009
Device	water chlorination by the flogenic	1	2015
Other	webinars	1	2016
Drug	week sc	1	2008
Drug	weekly oral cyclic antibiotic programme	1	2011
Drug	weileshu	1	2019
Drug	wf10	1	1999
Dietary Supplement	wheat polysaccharides	1	2015
Device	wira irradiation	1	2012
Procedure	with placement of a catheter	1	2018
Other	with visual cue	1	2018
Other	with visual cue/nurses informed	1	2018
Procedure	without placement of a catheter	1	2018
Other	without visual cue	1	2018
Other	without visual cue/nurses informed	1	2018
Other	wound assessment tool	1	2016
Other	wound dressing removal.	1	2016
Procedure	wound packing	1	2008
Device	wound protector	1	2010
Diagnostic Test	woundchek	1	2019
Behavioral	written information for parents	1	2006
Drug	xc221 100 mg	1	2018
Drug	xc221 200 mg	1	2018
Drug	xc8 100 mg	1	2018
Drug	xc8 20 mg	1	2018
Drug	xc8 200 mg	1	2018
Drug	xf-73	1	2019
Drug	xiaoer jiebiao oral liquid	1	2015
Dietary Supplement	xylitol	1	2008
Dietary Supplement	xylitol / bb12	1	2008
Drug	yallaferonâ®	1	2013
Drug	ying qiao san	1	2009
Drug	yps	1	2009
Drug	zanamivir	1	2011
Other	zeolite	1	2018
Drug	ziagen	1	2004
Drug	zidovudine (zdv)	1	2010
Drug	zidovudine/lamivudine (combivirâ®)	1	2006
Drug	zinc	1	2007
Drug	zmapp	1	2015
Drug	zti-01	1	2016
Drug	zyvoxâ®	1	2002
Drug	zyvoxâ® / linezolid	1	2002

Interventions over Time

Weekly studies for each intervention

Studies by Country

Country	Study_Count
United States	607
NA	161
France	78
Canada	52
China	52
Spain	40
Switzerland	37
United States|Puerto Rico	35
United Kingdom	33
United States|Canada	31
Germany	29
Taiwan	26
Thailand	21
Italy	19
Japan	19
Netherlands	18
Mexico	17
Russian Federation	17
Australia	14
Egypt	14
Korea, Republic of	14
Denmark	13
Israel	13
Sweden	13
Brazil	12
Belgium	11
Kenya	11
India	10
Turkey	10
Bangladesh	9
Finland	7
Greece	7
Norway	7
United States|Canada|Puerto Rico	7
Hong Kong	5
South Africa	5
United States|Tanzania	5
Vietnam	5
Bulgaria	4
Colombia	4
Croatia	4
Ethiopia	4
Iran, Islamic Republic of	4
Nigeria	4
Peru	4
United States|United Kingdom	4
Austria	3
Poland	3
Singapore	3
Tanzania	3
Australia|New Zealand	2
Belgium|France	2
Belgium|Spain	2
Chile	2
Hungary	2
Indonesia	2
Malaysia	2
Pakistan	2
Panama	2
Rwanda	2
Uganda	2
Ukraine	2
United States|Australia	2
United States|Australia|Canada|France|Germany|New Zealand|Puerto Rico|United Kingdom	2
United States|France	2
United States|New Zealand|Puerto Rico	2
Zambia	2
Algeria|Australia|Austria|Belgium|Bulgaria|Canada|Denmark|Finland|France|Germany|Greece|Ireland|Israel|Italy|Mexico|Netherlands|Norway|Poland|Portugal|Romania|Russian Federation|Saudi Arabia|Spain|Sweden|Switzerland|Turkey|United Kingdom	1
Argentina|Brazil|Canada|United Kingdom	1
Argentina|Brazil|Mexico|Peru|Russian Federation|South Africa|Thailand	1
Argentina|United States|Austria|Brazil|Chile|Germany|Latvia|Mexico|Poland|Russian Federation|Ukraine|United Kingdom	1
Australia|China|Denmark|Finland|France|Germany|Greece|Hong Kong|India|Italy|Philippines|Portugal|Saudi Arabia|South Africa|Spain|Switzerland|Taiwan|Turkey|United Kingdom	1
Australia|United Kingdom	1
Austria|Belgium|Bulgaria|Canada|Denmark|France|Germany|Greece|Hungary|Ireland|Italy|Netherlands|Poland|Serbia|Slovakia|Spain|Sweden|United Kingdom	1
Austria|Belgium|Bulgaria|France|Germany|Greece|Hungary|Ireland|Israel|Italy|Latvia|Lithuania|Netherlands|Poland|Romania|Russian Federation|South Africa|Spain|Ukraine|United Kingdom	1
Austria|Belgium|France|Germany|Saudi Arabia|Spain|United Kingdom	1
Austria|Belgium|France|Germany|Spain|United Kingdom	1
Austria|France|Germany|Italy	1
Austria|France|Greece|Italy|Poland|Russian Federation|United Kingdom	1
Austria|Germany|Italy|Russian Federation|Spain	1
Belarus|Russian Federation|Ukraine	1
Belgium|Australia|Bulgaria|Estonia|Hungary|Israel|Latvia|Malaysia|Philippines|Poland|Slovakia|Spain|Thailand|United Kingdom	1
Belgium|Bulgaria|Chile|Colombia|Croatia|Czechia|Estonia|Germany|Hungary|Israel|Latvia|Malaysia|Philippines|Poland|Slovakia|Spain|Thailand	1
Belgium|Canada	1
Belgium|Czech Republic|Lithuania	1
Belgium|France|Germany|Italy|Romania|Russian Federation|Spain|Switzerland|United Kingdom	1
Belgium|France|Germany|Portugal|Spain|Sweden|Switzerland|United Kingdom	1
Belgium|France|Germany|United Kingdom	1
Belgium|France|Italy|Lithuania	1
Belgium|France|Monaco	1
Belgium|Germany|Israel	1
Belgium|Mauritius|Moldova, Republic of	1
Benin	1
Benin|Canada|Ghana|Indonesia|Vietnam	1
Bosnia and Herzegovina	1
Botswana	1
Botswana|Kenya|Malawi|Mozambique|South Africa|Tanzania|Zimbabwe	1
Botswana|Tanzania|Zambia|Zimbabwe	1
Brazil|Cambodia|Cameroon|Ethiopia|India|Tanzania|Vietnam	1
Brazil|United States|Argentina|Colombia|Greece|Israel|Italy|United Kingdom	1
Bulgaria|China|Hong Kong|Korea, Republic of|New Zealand|Poland|Taiwan|United Kingdom	1
Bulgaria|Germany|Romania|Serbia	1
Bulgaria|United States|Austria|Estonia|Georgia|Hungary|Latvia|Moldova, Republic of|Romania|Russian Federation|Slovakia|Ukraine	1
Canada|Czech Republic|Egypt|France|Greece|Jordan|Portugal|Russian Federation|Spain|Switzerland|Turkey|United Kingdom	1
Canada|France	1
Canada|Netherlands	1
Canada|Russian Federation|Ukraine	1
Chile|United States|Argentina|Bulgaria|Croatia|Estonia|Germany|Hungary|Israel|Korea, Republic of|Latvia|Lithuania|Moldova, Republic of|Poland|Serbia	1
China|Hong Kong|Indonesia|Korea, Republic of|Malaysia|Taiwan	1
China|Hong Kong|Korea, Republic of|Taiwan|Vietnam	1
China|Korea, Republic of|Taiwan	1
China|Korea, Republic of|Vietnam	1
China|Pakistan|Philippines	1
Congo	1
Congo, The Democratic Republic of the	1
Costa Rica	1
Croatia|Czechia|Israel|Latvia|United States|Argentina|Australia|Austria|Belarus|Bosnia and Herzegovina|Brazil|Bulgaria|Canada|Colombia|Denmark|Estonia|Georgia|Germany|Greece|Hungary|Lithuania|Mexico|Netherlands|North Macedonia|Peru|Poland|Portugal|Puerto Rico|Romania|Russian Federation|Serbia|Slovakia|South Africa|Spain|Turkey|Ukraine|United Kingdom	1
Cuba	1
Czech Republic	1
Estonia|Russian Federation	1
Ethiopia|Rwanda	1
Fiji	1
France|Germany|Netherlands	1
France|Lithuania|Spain|United Kingdom	1
French Guiana	1
Gambia	1
Georgia	1
Georgia|Greece|Hungary|Latvia|Lithuania|Poland|Romania|Estonia|United States|Belarus|Bulgaria|Croatia|Czechia|Russian Federation|Slovakia|Ukraine	1
Germany|Israel|Italy	1
Germany|Netherlands	1
Germany|Poland	1
Germany|Switzerland	1
Germany|United Kingdom	1
Germany|United States|Australia|Canada|Denmark|France|Italy|Sweden|Switzerland|United Kingdom	1
Germany|United States|Belgium|Canada|France|Hong Kong|Italy|Puerto Rico|United Kingdom	1
Ghana	1
Guatemala	1
India|Malawi|South Africa|Tanzania|Uganda|Zambia|Zimbabwe	1
Iraq	1
Ireland	1
Italy|United States|Austria|Belgium|Denmark|France|Germany|Greece|Israel|Netherlands|Spain|United Kingdom	1
Kazakhstan|Russian Federation	1
Kenya|Malawi|South Africa|Tanzania|Uganda|Zimbabwe	1
Kenya|Tanzania|Thailand|Uganda	1
Kenya|Uganda	1
Kenya|Zimbabwe	1
Korea, Republic of|China|Taiwan	1
Lao People’s Democratic Republic	1
Latvia|Austria|Belgium|Denmark|France|Germany|Ireland|Italy|Netherlands|Portugal|Spain|Switzerland|United Kingdom	1
Latvia|United States|Argentina|Bulgaria|Canada|Chile|Czechia|Germany|Greece|Hungary|Lithuania|Mexico|Peru|Romania|Russian Federation|Ukraine	1
Lebanon	1
Lithuania|United States|Argentina|Bulgaria|Estonia|Germany|Hungary|Latvia|Peru|Romania|South Africa	1
Madagascar	1
Malawi	1
Malawi|South Africa	1
Malaysia|Philippines|Thailand|Vietnam	1
Moldova, Republic of	1
Norway|Sweden	1
Papua New Guinea	1
Poland|Russian Federation	1
Romania|Argentina|Belgium|Bulgaria|Estonia|France|Germany|Greece|Israel|Latvia|Lithuania|Russian Federation|South Africa|Spain	1
Romania|South Africa	1
Russian Federation|Sweden	1
Russian Federation|Ukraine	1
Russian Federation|United States|Canada|Croatia|Georgia|Germany|Poland|Ukraine	1
Russian Federation|Uzbekistan	1
Saudi Arabia	1
Sierra Leone	1
South Africa|Tanzania|Uganda|Zambia	1
South Africa|Uganda|Zambia	1
South Africa|United States|Brazil|Colombia|Estonia|Georgia|Germany|Hungary|Israel|Latvia|Mexico|Moldova, Republic of|Romania|Russian Federation|Serbia|Slovakia|Thailand	1
Spain|Switzerland|United Kingdom	1
Spain|United States|Austria|Belgium|Canada|France|Germany|Italy|Latvia|Luxembourg|Poland|Portugal|Romania|Switzerland	1
Sri Lanka	1
Sweden|Spain|United States|Argentina|Australia|Canada|France|Germany|Italy|Korea, Republic of|Mexico|Russian Federation|South Africa	1
Tunisia	1
United States|American Samoa|Australia	1
United States|Argentina|Australia|Austria|Belgium|Brazil|Bulgaria|Canada|Chile|Colombia|Czechia|Estonia|Finland|France|Germany|Hungary|Israel|Italy|Japan|Korea, Republic of|Latvia|Lithuania|Mexico|New Zealand|Panama|Poland|Russian Federation|South Africa|Spain|Sweden|Turkey|Ukraine|United Kingdom	1
United States|Argentina|Australia|Austria|Belgium|Brazil|Canada|Chile|China|Colombia|Croatia|Denmark|Estonia|Finland|France|Germany|Greece|Hungary|India|Italy|Korea, Republic of|Latvia|Lithuania|Mexico|Panama|Peru|Poland|Portugal|Romania|Russian Federation|Slovakia|South Africa|Spain|Sweden|Switzerland|Taiwan|Turkey|Ukraine|United Kingdom	1
United States|Argentina|Australia|Belarus|Belgium|Brazil|Bulgaria|Canada|Chile|Czechia|Germany|Greece|Hungary|Korea, Republic of|Mexico|New Zealand|Peru|Poland|Portugal|Russian Federation|Spain	1
United States|Argentina|Australia|Belgium|Brazil|Bulgaria|Chile|China|Croatia|Czechia|France|Germany|Greece|Hong Kong|Israel|Italy|Korea, Republic of|Mexico|Peru|Philippines|Poland|Romania|Russian Federation|South Africa|Spain|Taiwan|Turkey|Ukraine	1
United States|Argentina|Australia|Belgium|Brazil|Canada|Chile|France|Greece|Hungary|Italy|Mexico|Netherlands|Poland|Romania|Russian Federation|South Africa|Spain|Taiwan|United Kingdom	1
United States|Argentina|Australia|Belgium|Canada|France|Germany|Italy|Korea, Republic of|Mexico|Netherlands|Portugal|Romania|Russian Federation|South Africa|Spain|Taiwan|United Kingdom	1
United States|Argentina|Australia|Brazil|Germany|Mexico|New Zealand|Poland|Russian Federation|South Africa|Spain	1
United States|Argentina|Belarus|Bulgaria|Chile|Colombia|Georgia|Greece|Guatemala|Latvia|Lithuania|Mexico|Panama|Poland|Romania|Russian Federation|South Africa|Spain|Ukraine	1
United States|Argentina|Belarus|Bulgaria|Croatia|Estonia|Georgia|Hungary|Latvia|Lithuania|Mexico|Peru|Poland|Russian Federation|Serbia|Slovakia|South Africa|Spain|Ukraine	1
United States|Argentina|Belgium|Brazil|Chile|Colombia|Italy|Malaysia|Mexico|Portugal|Russian Federation|Singapore|South Africa|Spain|United Kingdom|Venezuela	1
United States|Argentina|Brazil|Bulgaria|Chile|Estonia|Georgia|Hungary|Korea, Republic of|Latvia|Mexico|Moldova, Republic of|Peru|Romania|Slovakia|Taiwan	1
United States|Argentina|Brazil|Bulgaria|Croatia|Czechia|Germany|Greece|Hungary|Israel|Japan|Korea, Republic of|Mexico|Poland|Portugal|Romania|Russian Federation|Serbia|Slovakia|Taiwan|Turkey|Ukraine	1
United States|Argentina|Brazil|Canada|Chile|Mexico	1
United States|Argentina|Brazil|Canada|Czechia|Germany|Hungary|Latvia|Peru|Slovakia|Ukraine	1
United States|Argentina|Brazil|Chile|Germany|Mexico|Peru|Poland|Romania|Russian Federation|Ukraine	1
United States|Argentina|Brazil|Colombia|Czechia|Germany|Hungary|Malaysia|Mexico|Norway|Poland|Portugal|Romania|South Africa|Spain|Sweden|United Kingdom	1
United States|Argentina|Bulgaria|Croatia|Czechia|France|Israel|Korea, Republic of|Mexico|Peru|Philippines|Poland|Romania|Russian Federation|South Africa|Spain|Turkey|Ukraine	1
United States|Argentina|Bulgaria|Croatia|Czechia|Germany|Israel|Italy|Korea, Republic of|Mexico|Peru|Poland|Romania|Russian Federation|Spain|Taiwan|Ukraine	1
United States|Argentina|Bulgaria|Croatia|Czechia|Hungary|India|Israel|Latvia|Malaysia|Mexico|Netherlands|Peru|Romania|Russian Federation|South Africa|Spain|Taiwan|Thailand|Ukraine	1
United States|Argentina|Bulgaria|Czech Republic|Estonia|France|Germany|Latvia|Lithuania|Romania|Russian Federation|South Africa|Ukraine	1
United States|Argentina|Canada|France|Italy|Mexico|Portugal|Puerto Rico|Russian Federation|South Africa|Spain|Thailand|United Kingdom	1
United States|Argentina|Chile|Costa Rica|Germany|Mexico|Netherlands|South Africa|Taiwan	1
United States|Argentina|Chile|Georgia|Latvia|Lithuania|Poland|Romania|South Africa|Spain	1
United States|Argentina|Georgia|Russian Federation|Serbia	1
United States|Argentina|Germany|Korea, Republic of|Romania|Spain	1
United States|Australia|Belgium|France|Israel|Italy|Korea, Republic of|Netherlands|New Zealand|Poland|United Kingdom	1
United States|Australia|Belgium|Germany|Italy|New Zealand|Russian Federation|United Kingdom	1
United States|Australia|Belgium|Israel|Netherlands|Russian Federation|Spain	1
United States|Australia|Bulgaria|Canada|Chile|Denmark|Finland|Germany|Hungary|Netherlands|New Zealand|Panama|Puerto Rico|South Africa|Spain|Sweden|Turkey|Ukraine|United Kingdom	1
United States|Australia|Canada|France|Germany|Italy|New Zealand|Puerto Rico|United Kingdom	1
United States|Australia|India|Italy|Romania|Ukraine	1
United States|Australia|Korea, Republic of|Taiwan	1
United States|Australia|New Zealand|United Kingdom	1
United States|Austria|Belgium|Canada|Chile|China|Denmark|Finland|France|Germany|Greece|Israel|Italy|Malaysia|Netherlands|Norway|Poland|Portugal|Saudi Arabia|Singapore|Slovakia|Spain|Sweden|Switzerland|United Kingdom	1
United States|Austria|Canada|Denmark|France|Germany|Ireland|Italy|Netherlands|Spain|United Kingdom	1
United States|Austria|France|Israel|Spain|United Kingdom	1
United States|Austria|Ireland	1
United States|Bahamas|Brazil|Puerto Rico	1
United States|Belarus|Belgium|Brazil|Estonia|France|Georgia|India|Israel|Latvia|Mexico|Russian Federation|Serbia|South Africa|Turkey|Ukraine	1
United States|Belarus|Belgium|Canada|Czechia|Estonia|France|Georgia|Germany|Israel|Latvia|Lithuania|Peru|Spain	1
United States|Belgium|Canada|France|Germany|Italy|Portugal|Spain|United Kingdom	1
United States|Belgium|Canada|Germany|Spain|Switzerland	1
United States|Belgium|Canada|Romania|Russian Federation|South Africa|Spain	1
United States|Belgium|Czechia	1
United States|Belgium|Germany|Ireland|Poland|Puerto Rico|United Kingdom	1
United States|Belgium|Germany|Italy|Taiwan	1
United States|Belgium|Germany|Puerto Rico|Spain	1
United States|Belgium|Italy|United Kingdom	1
United States|Belgium|Mexico|South Africa|Taiwan|Ukraine	1
United States|Belgium|United Kingdom	1
United States|Brazil	1
United States|Brazil|Bulgaria|Germany|Mexico|Poland|South Africa|Turkey	1
United States|Brazil|Canada	1
United States|Brazil|Colombia|Costa Rica|Ecuador|Mexico|Panama|Peru|Puerto Rico	1
United States|Brazil|Croatia|France|Germany|Greece|Guatemala|Israel|Italy|Japan|Korea, Republic of|Spain|Taiwan|Thailand|Turkey|United Kingdom	1
United States|Brazil|Hungary|Lithuania|Malaysia|Mexico|Romania|Russian Federation|South Africa|Spain|Turkey|Ukraine	1
United States|Brazil|Malawi|Peru|South Africa|Thailand|Zimbabwe	1
United States|Brazil|Mexico|Puerto Rico|South Africa	1
United States|Brazil|Peru|Switzerland	1
United States|Brazil|Puerto Rico|South Africa|Thailand	1
United States|Brazil|Puerto Rico|South Africa|Thailand|Uganda	1
United States|Bulgaria|China|Croatia|Hungary|Latvia|Mexico	1
United States|Bulgaria|Colombia|Greece|Norway|Poland|Ukraine|United Kingdom	1
United States|Bulgaria|Croatia|Estonia|Georgia|Hungary|Latvia|Romania|Russian Federation|Serbia|South Africa|Ukraine	1
United States|Bulgaria|Croatia|Greece|Hungary|Israel|Latvia|Peru|Poland|Romania|South Africa|Spain|Turkey|Ukraine	1
United States|Bulgaria|Czechia|Estonia|Georgia|Hungary|Latvia|Lithuania|Romania|Russian Federation|Ukraine	1
United States|Bulgaria|Czechia|Estonia|Georgia|Hungary|Latvia|Moldova, Republic of|Poland|Romania|Russian Federation|Serbia|Slovakia|South Africa|Ukraine	1
United States|Bulgaria|Czechia|Poland	1
United States|Bulgaria|Estonia|Hungary|Israel|Korea, Republic of|Latvia|Lithuania|Romania|Russian Federation|Slovakia|South Africa|Taiwan|Ukraine	1
United States|Bulgaria|France|India|Lebanon|Poland|Romania|Russian Federation	1
United States|Bulgaria|Germany|India	1
United States|Bulgaria|Germany|Lebanon|Poland|Russian Federation|Turkey	1
United States|Bulgaria|Hungary|Ukraine	1
United States|Bulgaria|India|Latvia|Lithuania|Romania	1
United States|Canada|Dominican Republic|Japan|Spain|Taiwan|Thailand	1
United States|Canada|Finland|Germany|Philippines|Thailand|United Kingdom	1
United States|Canada|Finland|Germany|Thailand	1
United States|Canada|France|Germany|Spain	1
United States|Canada|Netherlands|Puerto Rico	1
United States|China|Philippines|Taiwan	1
United States|China|South Africa|Spain	1
United States|Colombia|Czechia|France|Israel|Italy|Spain|Taiwan	1
United States|Colombia|France|Israel|Mexico|Philippines|Poland|Russian Federation|South Africa|Spain|Turkey	1
United States|Costa Rica|Panama|Puerto Rico	1
United States|Croatia|Israel|Latvia|Russian Federation|Spain|Ukraine	1
United States|Czechia|Greece|Hungary|Poland|Romania|Russian Federation|Spain|Taiwan|Turkey	1
United States|Czechia|Greece|Hungary|Poland|Romania|Russian Federation|Taiwan|Turkey	1
United States|Czechia|United Kingdom	1
United States|Finland|Mexico	1
United States|France|Germany|Spain	1
United States|France|Korea, Republic of|Sweden|Switzerland	1
United States|France|United Kingdom	1
United States|Georgia	1
United States|Germany|Poland	1
United States|Germany|Poland|Sweden	1
United States|Greece|Hungary|Mexico|Poland|Romania|Russian Federation|South Africa|Turkey|Ukraine	1
United States|Guatemala	1
United States|Guinea|Liberia|Sierra Leone	1
United States|Hungary|Latvia|Poland|Serbia	1
United States|India	1
United States|India|Korea, Republic of|Romania|Taiwan	1
United States|India|Panama	1
United States|Israel	1
United States|Israel|South Africa	1
United States|Italy	1
United States|Italy|Puerto Rico|	1
United States|Kenya|South Africa|Thailand	1
United States|Malawi|South Africa|Zambia|Zimbabwe	1
United States|Mexico	1
United States|Peru|South Africa	1
United States|Puerto Rico|South Africa	1
United States|Slovakia|Spain|Taiwan	1
United States|South Africa|Taiwan|Thailand	1
United States|Taiwan|Argentina|Australia|Belgium|Canada|France|Germany|Italy|Mexico|Peru|Poland|Portugal|Romania|Russian Federation|Spain|Switzerland|United Kingdom	1
United States|Ukraine	1
United States|Zimbabwe	1

Sites per Study

Site_count	Study_Count
1	1027
2	113
3	56
4	45
5	50
6	27
7	26
8	17
9	22
10	12
11	20
12	13
13	11
14	15
15	18
16	13
17	14
18	7
19	12
20	6
21	12
22	12
23	3
24	4
25	6
26	7
27	5
28	8
29	2
30	8
31	5
32	4
33	9
34	8
35	6
36	2
37	4
38	4
39	6
40	7
41	1
42	3
43	6
44	2
45	6
46	6
47	3
48	3
49	5
50	9
51	4
52	5
53	2
54	4
55	1
56	2
57	4
58	1
59	4
60	3
61	2
62	3
66	3
67	2
68	2
69	4
70	1
71	4
72	2
73	1
74	1
75	1
76	4
78	3
80	1
84	4
85	1
89	1
90	1
91	1
92	2
93	2
94	1
96	1
100	1
104	1
105	1
106	1
108	1
115	1
118	1
120	1
123	1
126	1
137	1
178	1
179	1
180	1
181	1
187	1
205	1
211	1
277	1
617	1

Phase

Phase	Study_Count
N/A	555
Phase 3	384
Phase 2	308
Phase 4	273
Phase 1	176
Phase 1/Phase 2	47
Phase 2/Phase 3	37
Early Phase 1	8

Number of Arms

Number_of_Arms	Count_of_Studies
1	305
2	868
3	160
4	83
5	25
6	18
7	4
8	12
10	3
11	2
12	1
13	1
25	1
NA	305

Number of Updates

Count of Versions	Count of Studies
1	233
2	224
3	209
4	210
5	157
6	113
7	80
8	70
9	56
10	53
11	41
12	40
13	41
14	27
15	14
16	23
17	15
18	16
19	17
20	14
21	7
22	8
23	11
24	6
25	8
26	6
27	4
28	2
30	4
31	4
32	6
33	5
34	4
35	3
36	2
37	2
38	1
40	2
41	3
42	3
43	2
44	4
45	2
47	2
48	1
49	2
50	1
51	1
55	3
56	1
62	1
63	1
65	2
68	2
70	1
72	2
73	2
87	1
88	1
93	1
94	1
96	1
114	1
118	1
121	1
125	1
189	1
197	1
203	1
242	1
421	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	13882	1555	8.927331
Contacts/Locations	6168	1291	4.777692
Recruitment Status	2359	1278	1.845853
None (earliest Version on record)	1788	1788	1.000000
Study Design	1610	1064	1.513158
Outcome Measures	1499	774	1.936692
Arms	1170	696	1.681034
Interventions	1170	696	1.681034
Eligibility	1155	644	1.793478
Study Identification	1126	677	1.663220
Study Description	1063	617	1.722852
Sponsor/Collaborators	1036	674	1.537092
Oversight	738	605	1.219835
Conditions	624	379	1.646438
More Information	606	248	2.443548
References	527	378	1.394180
Results	356	356	1.000000
IPDSharing	255	215	1.186047
Baseline Characteristics	148	125	1.184000
Reported Adverse Events	126	99	1.272727
Documents	117	111	1.054054
Participant Flow	109	92	1.184783
Results Submission Events	105	105	1.000000
2020 Study Status	4	3	1.333333
2020Recruitment Status	2	2	1.000000
2020 Baseline Characteristics	1	1	1.000000
2020 Documents	1	1	1.000000
Quality Control Review has not concludedReturned: April 28	1	1	1.000000
Quality Control Review has not concludedReturned: February 25	1	1	1.000000
Quality Control Review has not concludedReturned: June 4	1	1	1.000000
Quality Control Review has not concludedReturned: March 9	1	1	1.000000
Quality Control Review has not concludedReturned: May 12	1	1	1.000000
Quality Control Review has not concludedReturned: May 13	1	1	1.000000
Quality Control Review has not concludedReturned: May 27	1	1	1.000000
Quality Control Review has not concludedReturned: May 29	1	1	1.000000

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	1.000	1.000	2.0000	8.000	7.0000	2.0000	10.0000	6.0000
1st Qu.	10.000	60.000	20.0000	20.000	47.0000	50.0000	151.2500	72.5000
Median	15.000	221.000	32.0000	56.000	100.0000	154.0000	350.0000	169.0000
Mean	201.375	1566.178	55.6506	2798.267	220.3213	517.9189	758.4603	504.7978
3rd Qu.	78.500	718.000	56.0000	120.000	210.0000	380.0000	711.5000	393.0000
Max.	1306.000	126750.000	500.0000	118621.000	3101.0000	5659.0000	12793.0000	22089.0000

Trial Group Type

group_type	Group_Count
Experimental	1843
Active Comparator	789
Placebo Comparator	356
NA	305
No Intervention	203
Other	108
Sham Comparator	13

Intervention Model

intervention_model	Study_Count
Parallel Assignment	1140
Single Group Assignment	372
NA	164
Crossover Assignment	51
Sequential Assignment	34
Factorial Assignment	27

Primary Purpose

primary_purpose	Study_Count
Treatment	1036
Prevention	492
Diagnostic	57
Basic Science	53
Health Services Research	37
Other	34
Supportive Care	32
NA	30
Screening	15
Device Feasibility	1
Educational/Counseling/Training	1

Observational Studies

Studies by Country

Country	Study_Count
United States	188
France	74
NA	65
China	35
Spain	17
United Kingdom	16
Germany	15
Switzerland	14
Canada	12
Italy	12
Taiwan	12
Denmark	11
Israel	11
Netherlands	9
Thailand	9
Brazil	8
India	7
Austria	6
Egypt	6
Korea, Republic of	6
Japan	5
United States|Canada	5
Turkey	4
Australia	3
Belgium	3
Congo, The Democratic Republic of the	3
Finland	3
Hong Kong	3
Indonesia	3
Martinique	3
Norway	3
Russian Federation	3
Sweden	3
Tanzania	3
Uganda	3
Argentina	2
Cambodia	2
Mexico	2
Pakistan	2
Philippines	2
Poland	2
Argentina|Bangladesh|Brazil|Canada|Chile|China|Colombia|India|Iran, Islamic Republic of|Kazakhstan|Kyrgyzstan|Malaysia|Pakistan|Palestinian Territory, occupied|Peru|Philippines|Poland|Russian Federation|Saudi Arabia|South Africa|Sweden|Tanzania|Turkey|United Arab Emirates|Zimbabwe	1
Argentina|Barbados|Colombia|Sri Lanka|Thailand	1
Argentina|Chile|Colombia|Ecuador|Mexico|Peru|Uruguay	1
Austria|Belgium|Bulgaria|Croatia|Czech Republic|Denmark|Estonia|Finland|France|Germany|Greece|Hungary|Ireland|Italy|Latvia|Lithuania|Netherlands|Norway|Poland|Portugal|Romania|Russian Federation|Serbia|Slovenia|Spain|Sweden|Switzerland|Turkey|Ukraine|United Kingdom	1
Austria|Germany	1
Bangladesh	1
Belarus	1
Belgium|Cambodia|Congo, The Democratic Republic of the	1
Belgium|Czechia|Estonia|France|Italy|Netherlands|Romania|Serbia|Spain|United Kingdom	1
Belgium|Netherlands|United Kingdom	1
Bolivia|Chile	1
Botswana	1
Brazil|France|Greece|Italy|Russian Federation|Spain	1
Burkina Faso	1
Côte D’Ivoire|Indonesia|Mali|Nepal	1
Canada|Philippines	1
Croatia|Germany|Italy	1
Ecuador	1
Finland|Ireland|Netherlands|Portugal|Switzerland	1
Finland|Netherlands|Spain|United Kingdom	1
France|Belgium|Germany|Greece|Italy|Netherlands|Portugal|Spain|Turkey|United Kingdom	1
France|Germany|Italy|Spain|United Kingdom	1
France|Hungary|Italy|Poland|Spain	1
Gambia	1
Germany|Hungary|Norway|United Kingdom	1
Germany|Italy|United Kingdom	1
Greece	1
Hungary	1
Iran, Islamic Republic of	1
Ireland	1
Israel|Netherlands	1
Israel|United Kingdom	1
Kenya	1
Latvia	1
Lithuania	1
Moldova, Republic of	1
Mozambique	1
Myanmar	1
Peru	1
Portugal	1
Romania	1
Rwanda|South Africa	1
Sierra Leone	1
Suriname	1
Swaziland	1
Uganda|United Kingdom	1
United States|Argentina|Austria|Belgium|Canada|China|Denmark|Germany|Japan|Switzerland	1
United States|Australia|Brazil|Canada|Zimbabwe	1
United States|Australia|China|Colombia	1
United States|Austria|Israel|Switzerland|United Kingdom	1
United States|Brazil|Peru|South Africa	1
United States|Canada|Israel|Singapore|United Kingdom	1
United States|Denmark	1
United States|Dominican Republic|Haiti|Peru|Puerto Rico|South Africa	1
United States|Greece	1
United States|Greece|Italy|United Kingdom	1
United States|India	1
United States|Malawi|South Africa|Tanzania|Uganda	1
United States|Puerto Rico	1
Vietnam	1
Zimbabwe	1

Sites per Study

Site_count	Study_Count
1	483
2	52
3	17
4	12
5	7
6	7
7	6
8	3
9	2
10	4
11	3
12	3
13	2
14	3
15	5
16	2
17	3
18	2
19	1
20	2
21	4
22	2
23	3
24	3
25	2
26	1
27	3
30	2
33	1
34	1
35	1
36	2
38	2
43	2
45	1
52	2
59	2
69	1
163	1
538	1

Number of Updates

Count of Versions	Count of Studies
1	135
2	139
3	108
4	63
5	61
6	24
7	17
8	15
9	14
10	5
11	9
12	7
13	5
14	3
15	3
16	3
17	5
19	4
20	1
22	2
23	2
24	3
25	1
27	1
28	1
29	1
30	1
37	1
38	1
39	1
41	1
42	1
54	1
60	1
62	1
63	1
70	1
74	1
80	1
89	1
94	1
95	1
98	1
100	1
123	1
124	1
126	1
135	1
147	1
151	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	3999	521	7.675624
Contacts/Locations	1034	387	2.671835
Study Description	765	178	4.297753
None (earliest Version on record)	656	656	1.000000
Recruitment Status	629	393	1.600509
Study Design	605	354	1.709040
Eligibility	374	178	2.101124
Sponsor/Collaborators	272	189	1.439153
Study Identification	238	164	1.451220
Outcome Measures	222	157	1.414013
Conditions	190	134	1.417910
Oversight	155	127	1.220472
References	152	83	1.831325
Groups	139	105	1.323810
Interventions	139	105	1.323810
IPDSharing	35	32	1.093750
Results	33	33	1.000000
More Information	23	18	1.277778
Baseline Characteristics	10	8	1.250000
Documents	5	5	1.000000
Results Submission Events	5	5	1.000000
Reported Adverse Events	4	3	1.333333
Participant Flow	3	2	1.500000

Enrollment Metrics

Measure	Observational
Min	0.00
1st Qu	100.00
Median	250.00
Mean	11672.87
3rd Qu	908.00
Max	1660652.00

Observation Model

observational_model	Study_Count
Cohort	342
Case-Only	101
NA	68
Case-Control	46
Other	43
Case Control	28
Ecologic or Community	12
Natural History	5
Case Control, Natural History	3
Defined Population, Natural History	3
Case-Crossover	2
Family-Based	2
Defined Population	1

Time Perspective

time_perspective	Study_Count
Prospective	443
Retrospective	104
NA	42
Cross-Sectional	39
Other	19
Longitudinal, Prospective	8
Longitudinal, Retrospective	1

Registries

Studies by Country

Country	Study_Count
China	5
France	5
Italy	4
United States	4
Turkey	3
Belgium	2
Canada	2
Colombia	2
Spain	2
Sweden	2
Austria	1
Chile	1
Denmark	1
Denmark|Norway|Sweden	1
Ethiopia	1
Germany	1
Hong Kong|Korea, Republic of|Singapore|Taiwan|Thailand	1
NA	1
Singapore	1
Switzerland	1
Taiwan	1
United States|Australia|Belgium|Germany|Italy|New Zealand|Russian Federation|United Kingdom	1
United States|Australia|Canada|France|Germany|Italy|New Zealand|Puerto Rico|Spain|United Kingdom	1

Sites per Study

Site_count	Study_Count
1	33
2	2
5	1
6	2
8	1
14	1
16	1
48	1
54	1
138	1

Number of Updates

Count of Versions	Count of Studies
1	6
2	17
3	10
4	3
5	2
6	1
7	1
8	1
13	1
26	1
35	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	143	38	3.763158
Contacts/Locations	72	28	2.571429
None (earliest Version on record)	44	44	1.000000
Recruitment Status	28	23	1.217391
Study Design	22	17	1.294118
Eligibility	15	12	1.250000
Study Description	13	11	1.181818
Oversight	11	10	1.100000
Study Identification	11	9	1.222222
Sponsor/Collaborators	10	6	1.666667
Conditions	9	6	1.500000
Outcome Measures	7	7	1.000000
Groups	6	6	1.000000
Interventions	6	6	1.000000
References	3	2	1.500000
IPDSharing	2	2	1.000000

Enrollment Metrics

Measure	Registries
Min	1.000
1st Qu	138.750
Median	472.000
Mean	1323.386
3rd Qu	1014.500
Max	15926.000

Registry Model

observational_model	Study_Count
Cohort	27
Case-Control	7
Other	5
Case-Only	4
Case-Crossover	1

Time Perspective

time_perspective	Study_Count
Prospective	40
Cross-Sectional	2
Other	2

Follow-up

target_duration	Study_Count
5 Years	4
6 Months	4
1 Year	3
2 Weeks	3
30 Days	3
1 Day	2
10 Years	2
18 Years	2
2 Years	2
3 Months	2
3 Weeks	2
4 Weeks	2
1 Month	1
12 Months	1
14 Days	1
24 Months	1
28 Days	1
3 Years	1
31 Years	1
4 Months	1
4 Years	1
41 Weeks	1
60 Days	1
7 Months	1
8 Days	1